Lasertherapy and Biosilicate/magnesium/collagen composites, used in association or isolated: in vitro and in vivo biological evaluation in bone tissue

• Grant number: 14/20546-0
• Support Opportunities: Regular Research Grants
• Start date: April 01, 2015
• End date: March 31, 2017
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Ana Claudia Muniz Renno
• Grantee: Ana Claudia Muniz Renno
• Host Institution: Instituto de Saúde e Sociedade (ISS). Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Santos , SP, Brazil
• Associated researchers: Paulo Sérgio Bossini

Abstract

During the process of boné repair, 5 to 10% of the fractures culminate in abnormal consolidation. In this context, many treatments have been developing try to improve the process of bone healing, including biomaterials and low level laser therapy. In this context, this project has the aim of investigating the effects of composites of Biosilicate/ Collagen and magnesium and Lasertherapy, used associated or isolated in the process of bone healing. For this purpose, in vitro and in vivo tests (in a model of tibial bone defects in rats) will be performed. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PAIVA MAGRI, ANGELA MARIA; FERNANDES, KELLY ROSSETTI; KIDO, HUELITON WILIAN; FERNANDES, GABRIELA SODANO; FERMINO, STEPHANIE DE SOUZA; GABBAI-ARMELIN, PAULO ROBERTO; CORREA BRAGA, FRANSCISCO JOSE; GOES, ANTIA PEREIRADE; DOS SANTOS PRADO, JOSE LUCAS; GRANITO, RENATA NEVES; et al. Bioglass/PLGA associated to photobiomodulation: effects on the healing process in an experimental model of calvarial bone defect. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, v. 30, n. 9, SEP 2019. (14/20546-0)

PAIVA MAGRI, ANGELA MARIA; FERNANDES, KELLY ROSSETTI; ASSIS, LIVIA; KIDO, HUELITON WILIAN; AVANZI, INGRID REGINA; MEDEIROS, MATHEUS DA CRUZ; GRANITO, RENATA NEVES; CORREA BRAGA, FRANCISCO JOSE; MUNIZ RENNO, ANA CLAUDIA. Incorporation of collagen and PLGA in bioactive glass: in vivo biological evaluation. International Journal of Biological Macromolecules, v. 134, p. 869-881, AUG 1 2019. (14/20546-0)