Evaluation of a water soluble Curcumin preparation against toxicity induced by antineoplásic drug cisplatin: possible protective effects in vitro and in vivo, and identify changes in Tp53 gene expression

• Grant number: 08/10482-4
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: April 01, 2009
• End date: September 30, 2011
• Field of knowledge: Biological Sciences - Genetics - Mutagenesis
• Principal Investigator: Lusânia Maria Greggi Antunes
• Grantee: Leonardo Meneghin Mendonça
• Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MENDONCA, LEONARDO MENEGHIN; MACHADO, CARLA DA SILVA; CORREIA TEIXEIRA, CRISTIANE CARDOSO; PEDRO DE FREITAS, LUIS ALEXANDRE; PIRES BIANCHI, MARIA LOURDES; GREGGI ANTUNES, LUSANIA MARIA. Comparative study of curcumin and curcumin formulated in a solid dispersion: Evaluation of their antigenotoxic effects. GENETICS AND MOLECULAR BIOLOGY, v. 38, n. 4, p. 490-498, 2015. (08/10482-4)

MENDONCA, LEONARDO MENEGHIN; MACHADO, CARLA DA SILVA; CORREIA TEIXEIRA, CRISTIANE CARDOSO; PEDRO DE FREITA, LUIS ALEXANDRE; PIRES BIANCHI, MARIA DE LOURDES; GREGGI ANTUNES, LUSANIA MARIA. Curcumin reduces cisplatin-induced neurotoxicity in NGF-differentiated PC12 cells. NeuroToxicology, v. 34, p. 205-211, JAN 2013. (08/10482-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

MENDONÇA, Leonardo Meneghin. Evaluation of a water-soluble curcumin formulation against toxicity induced by antineoplasic drug cisplatin: the possible protective effects in vitro and in vivo, and modulation of Tp53 gene expression. 2012. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (PCARP/BC) Ribeirão Preto.