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Gestational evaluation in patients with dermatomyositis / polymyositis

Grant number: 11/15517-3
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2012
Effective date (End): January 31, 2013
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal researcher:Samuel Katsuyuki Shinjo
Grantee:Larissa Sayuri Missumi
Home Institution: Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil


Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of chronic autoimmune disease, systemic, associated with high morbidity and functional disability. Concerning to the clinical and histopathological features, the MII can be classified in polymyositis (PM), dermatomyositis (DM), juvenile dermatomyositis, inclusion body myositis, myositis associated with malignancy and myositis associated with other collagen diseases.Until now, the studies in the literature that describe pregnancy in DM / PM are mainly limited to case reports or series. This is because of DM / PM:a) be a rare systemic autoimmune disease;b) affect mainly individuals outside the age of fertility (45~55 years old).Consequently, evaluation and behavior of gestation in MII activity or remission of the disease and vice-versa is still controversial in the literature.Therefore, the few studies of pregnancy in DM / PM has motivated us to extend the approach of this topic in our population of DM / PM Service followed at tertiary composed of large samples.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
LARISSA SAYURI MISSUMI; FERNANDO HENRIQUE CARLOS DE SOUZA; JOELMA QUEIROZ ANDRADE; SAMUEL KATSUYUKI SHINJO. Desfechos da gestação em pacientes com dermatomiosite e polimiosite. REVISTA BRASILEIRA DE REUMATOLOGIA, v. 55, n. 2, p. 95-102, Abr. 2015.

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