Prevalence and clinical significance of hippocampal atrophy Juvenile Systemic Lupus Erythematosus

• Grant number: 12/08026-6
• Support Opportunities: Scholarships in Brazil - Master
• Start date: August 01, 2012
• End date: July 31, 2014
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Simone Appenzeller
• Grantee: Renata Barbosa
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 08/02917-0 - Blood and cerebrospinal fluid biomarkers associated with structural and functional central nervous system abnormalities in systemic lupus erythematosus, AP.JP

Abstract

Systemic lupus erythematoso (SLE) is a chronic autoimmune disease affecting multiple systems. Of unknown etiology, affects predominantly women between 15 and 50 years. Central nervous system involvement is associated with increased morbi-mortality. We have previously shown hippocampal atrophy in adult SLE patients, however the prevalence and clinical significance of hippocampal atrophy in children has never been studied. The aim of this study is to determine the prevalence and clinical significance of hippocampal atrophy in juvenil-onset SLE.

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

BARBOSA, Renata. Evaluation of the prevalence of hippocampal atrophy and factors associated in childhood - onset systemic lupus erythematosus. 2014. Master's Dissertation - Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas Campinas, SP.