Systemic lupus erythematoso (SLE) is a chronic autoimmune disease affecting multiple systems. Of unknown etiology, affects predominantly women between 15 and 50 years. Central nervous system involvement is associated with increased morbi-mortality. We have previously shown hippocampal atrophy in adult SLE patients, however the prevalence and clinical significance of hippocampal atrophy in children has never been studied. The aim of this study is to determine the prevalence and clinical significance of hippocampal atrophy in juvenil-onset SLE.
News published in Agência FAPESP Newsletter about the scholarship: