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Evaluation of the in vitro fermentation of passion fruit peel and its role in intestinal inflammation

Grant number: 12/24262-1
Support Opportunities:Scholarships abroad - Research Internship - Doctorate
Effective date (Start): July 01, 2013
Effective date (End): October 31, 2013
Field of knowledge:Health Sciences - Nutrition
Principal Investigator:Mário Roberto Maróstica Junior
Grantee:Cinthia Baú Betim Cazarin
Supervisor: Julio Juan Gálvez Peralta
Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Research place: Universidad de Granada (UGR), Spain  
Associated to the scholarship:10/16752-3 - Assessment of consumption of the peel of Passiflora edulis and its impact on intestinal inflammation in rats with ulcerative colitis., BP.DR


The nutritional and functional potential of agro-industrial waste has increased over the years. Brazilian native fruits such as passion fruit has its peel rich in fiber and phenolic compounds. The consumption of such industrial byproduct is directly related to decreased incidence of chronic diseases. The fermentation of dietary fiber favors microbial modulation, in particular increase of colonies of beneficial lactobacilli and bifidobacteria. Among the final products generated by fermentative process are the chain fatty acids (SCFA) which, besides being used as an energy source for enterocytes has anti-inflammatory action. Phenolic compounds present in these fed are excellent natural antioxidants, which can improve antioxidant status in vivo. In addition these compounds may also present among other effects, anti-inflammatory action. In this regard, the evaluation of passion fruit peel fermentation in vitro, could help identify optimal concentration to promote microbial modulation and increased production of SCFA. As well as, make it possible to evaluate the bioavailability of certain phenolic compounds present in the food matrix and the effect of the intake of the peel in the modulation of inflammatory mediators present in ulcerative colitis. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BETIM CAZARIN, CINTHIA BAU; RODRIGUEZ-NOGALES, ALBA; ALGIERI, FRANCESCA; PILAR UTRILLA, M.; ELENA RODRIGUEZ-CABEZAS, M.; GARRIDO-MESA, JOSE; GUERRA-HERNANDEZ, EDUARDO; DE CAMPOS BRAGA, PATRICIA APARECIDA; REYES REYES, FELIX GUILLERMO; MAROSTICA, JR., MARIO ROBERTO; et al. Intestinal anti-inflammatory effects of Passiflora edulis peel in the dextran sodium sulphate model of mouse colitis. Journal of Functional Foods, v. 26, p. 565-576, . (12/24262-1)

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