In vitro bioaccessibility of transgenic and non-transgenic soybeans using automated microdialysis-based system and filtration

• Grant number: 14/19369-7
• Support Opportunities: Scholarships abroad - Research Internship - Master's degree
• Start date: December 08, 2014
• End date: May 22, 2015
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Marco Aurelio Zezzi Arruda
• Grantee: Monica Alejandra Herrera Agudelo
• Supervisor: Manuel Miró Lladó
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Institution abroad: Universitat de les Illes Balears (UIB), Spain
• Associated to the scholarship: 13/02809-1 - In-vitro bioaccessibility study of some important biological metals in transgenic and non-transgenic soybean, BP.MS

Abstract

This project consists of nutritional comparative study between non-transgenic (Glicine max (L). Merril) and Round Ready® transgenic soybean, by evaluating the bioaccessibility, by means of differentiating bioacessible fractions, through automated system, of essential elements, such as Cu, Fe, Mn and Zn. The implementation of the referred automated methodology is performed by the research group in flow injection analysis and trace analysis (FI-TRACE) from the University of the Balearic Islands, simulating human digestion using microdialysis membrane, synthetic intestinal flows and passive diffusion of metal through the stomach and intestinal epithelium. Then, the system mimetizes the fraction of ingested bioaccessible elements, available for subsequent absorption. (AU)