Survey of American Visceral Leishmaniasis control's actions in Araçatuba and Birigüi cities using dynamic's transmission models

• Grant number: 14/06518-4
• Support type: Scholarships in Brazil - Doctorate
• Effective date (Start): January 01, 2015
• Effective date (End): September 30, 2018
• Field of knowledge: Health Sciences - Collective Health - Epidemiology
• Cooperation agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal researcher: Francisco Chiaravalloti Neto
• Grantee: Danielle Nunes Carneiro Castro Costa
• Home Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The zoonotic visceral leishmaniasis is the most severe clinical form of leishmaniasis and is considered an emerging disease by the World Health Organization. In São Paulo, the first autochthonous case was detected in 1998, in the same way that expansion occurs into urban areas all over Brazil since the 1980s, the disease has expanded to other municipalities' urban areas of the São Paulo, representing a major problem public health. Previous studies have been correlated the incidence of human disease with occurrence of canine zoonotic visceral leishmaniasis. One of the main strategies to control the disease is culling infected dogs. However, despite efforts to control, the disease's incidence remains high in Brazil. This project aims to point out the socio-epidemiologic and in applications of control measures differences among municipalities of Araçatuba and Birigüi. The control will be assessed based on their actions: relative importance of covering canine tracking, effectiveness of serological diagnosis and the delay between the diagnosis and the canine sacrifice, and effectiveness of canine zoonotic visceral leishmaniasis elimination as a control strategy. The study will analyse both the population of domestic dogs as community dogs, using for this serologic surveys and experiments in capture-mark-recapture. The result of analyses will be putting in a dynamic's models of zoonotic transmission of canine visceral leishmaniasis associated with cost-effectiveness for assess the control actions directed to canine disease in order to determine the best control effort at the lowest possible cost. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MORALEJO BERMUDI, PATRICIA MARQUES; CARNEIRO CASTRO COSTA, DANIELLE NUNES; NUNES, CANIS MARONI; TOLEZANO, JOSE EDUARDO; HIRAMOTO, ROBERTO MITSUYOSHI; COLEBRUSCO RODAS, LILIAN APARECIDA; CIPRIANO, RAFAEL SILVA; BLANGIARDO, MARTA; CHIARAVALLOTI-NETO, FRANCISCO. Canine serological survey and dog culling ant its relationship with human visceral leishmaniasis in an endemic urban area. BMC INFECTIOUS DISEASES, v. 20, n. 1 JUN 5 2020. Web of Science Citations: 0.

CARNEIRO CASTRO COSTA, DANIELLE NUNES; MORALEJO BERMUDI, PATRICIA MARQUES; COLEBRUSCO RODAS, LILIAN APARECIDA; NUNES, CARIS MARONI; HIRAMOTO, ROBERTO MITSUYOSHI; TOLEZANO, JOSE EDUARDO; CIPRIANO, RAFAEL SILVA; DINIZ CARDOSO, GRAZIELA CANDIDO; CODECO, CLAUDIA TORRES; CHIARAVALLOTI-NETO, FRANCISCO. Human visceral leishmaniasis and relationship with vector and canine control measures. Revista de Saúde Pública, v. 52, 2018. Web of Science Citations: 1.

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

COSTA, Danielle Nunes Carneiro Castro. Visceral leishmaniasis in the municipalities of Araçatuba and Birigui, state of São Paulo, Brazil. 2018. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Saúde Pública São Paulo.