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Diet and overweight in adolescents from São Paulo - outlook of the last decade and interaction with polymorphisms

Grant number: 16/07711-8
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): July 01, 2016
Effective date (End): September 08, 2018
Field of knowledge:Health Sciences - Nutrition - Nutritional Analysis of Population
Principal researcher:Regina Mara Fisberg
Grantee:Jaqueline Lopes Pereira França
Home Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated scholarship(s):17/02480-0 - Diet quality, obesity, and cardiometabolic risk factors in adolescents living in São Paulo and in the USA: differences and similarities, BE.EP.DR


The prevalence of overweight in adolescents is increasing in parallel with changes in lifestyle. The understanding of nutritional status over time and associated factors, such as diet, is essential to develop effective actions in health. Additionally, there are gaps in the understanding of gene-diet relationships that may be relevant to understand the mechanisms regulating body weight, identifying individuals who are more susceptible to a particular intervention or exposure. The aim of the project is to investigate the diet, overweight and the effects of single nucleotide polymorphisms (SNPs) associated with adiposity in adolescents of São Paulo city. Data are from a cross-sectional population-based survey among a representative sample of adolescents living in Sao Paulo, Brazil (ISA-Capital Survey) in 2003, 2008, and 2015. Socioeconomic, anthropometric and lifestyle data were collected on households or by telephone. Food consumption data were obtained by two 24 hours dietary recalls. SNPs in/near BMI-related genes and associated with diet interactions will be evaluated in adolescents. Trends across the years will be evaluated in panel data, considering the complexity of the sample. Logistic regression models will be used to investigate the association between diet and SNPs with nutritional status. Structural equation models will be used to evaluate the relationship between SNPs with diet predicting overweight.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PEREIRA, JAQUELINE LOPES; DOS SANTOS VIEIRA, DIVA ALIETE; GOI PORTO ALVES, MARIA CECILIA; GALVAO CESAR, CHESTER LUIS; GOLDBAUM, MOISES; FISBERG, REGINA MARA. Excess body weight in the city of SAo Paulo: panorama from 2003 to 2015, associated factors and projection for the next years. BMC PUBLIC HEALTH, v. 18, DEC 3 2018. Web of Science Citations: 1.
PEREIRA, JAQUELINE LOPES; FELIX, PAULA VICTORIA; MATTEI, JOSIEMER; FISBERG, REGINA MARA. Differences over 12 Years in Food Portion Size and Association with Excess Body Weight in the City of SAo Paulo, Brazil. NUTRIENTS, v. 10, n. 6 JUN 2018. Web of Science Citations: 0.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
FRANÇA, Jaqueline Lopes Pereira. Diet, excess body weight and cardiometabolic risk factors in the population of São Paulo city: panorama 2003 - 2015. 2018. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Saúde Pública São Paulo.

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