High-intensity intermittent training and anti-inflammatory response

• Grant number: 16/12145-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2016
• End date: June 30, 2017
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Fábio Santos de Lira
• Grantee: Thaislaine dos Santos
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

The regular practice of aerobic exercise when performed continuously at moderate intensity (~ 65% VO2 peak), is closely related to anti-inflammatory and anti-atherogenic, also further the reduction of fat deposits, preventing this way the overweight frame / obesity. In contrast, there is a growing practice of aerobic exercise intermittently, at high intensity (~ 100% of the maximum speed) in order to reduce deposits of fat, as well as improved metabolic condition (glycemic control and dyslipidaemia). However, it is incipient knowledge of the anti-inflammatory response against intermittent training programs high intensity. The objective of this study is to evaluate the acute and chronic anti-inflammatory response against to the realization of high-intensity interval training (HIIT: the English term for high-intensity intermittent training). To answer this question, male subjects will be recruited, eutrophic, aged 18 and 30, which will be randomized into three groups: 1) control group (not perform physical training); 2) continued training group (perform moderate continuous training, 65% of peak VO2, 5km per session 3x per week); 3) intermittent training group of high intensity (perform high-intensity intermittent training, 100% of the maximum speed, 1 minutes of exercise and 1 minute pause passive, 5km, 3x per week). The training programs will last six weeks. The project will answer the following questions: 1) evaluate the inflammatory response (TNF-±, IL-6 and IL-10) Acute and chronic front of different exercise training programs. In addition, the metabolic response (glucose, lactate and free fatty acids) will also be evaluated.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LIRA, FABIO SANTOS; DOS SANTOS, THAISLAINE; CALDEIRA, RENAN SANTOS; INOUE, DANIELA S.; PANISSA, VALERIA L. G.; CABRAL-SANTOS, CAROLINA; CAMPOS, EDUARDO Z.; RODRIGUES, BRUNO; MONTEIRO, PAULA A.. Short-Term High- and Moderate-Intensity Training Modifies Inflammatory and Metabolic Factors in Response to Acute Exercise. FRONTIERS IN PHYSIOLOGY, v. 8, OCT 31 2017. (15/12979-7, 16/16712-8, 15/11302-3, 16/12145-1)

DOS SANTOS, THAISLAINE; LIRA, FABIO SANTOS; ANTUNES, BARBARA MOURA. Interleukin-15 and creatine kinase response to high-intensity intermittent exercise training. SPORT SCIENCES FOR HEALTH, v. 16, n. 3, p. 479-484, SEP 2020. (16/12145-1)