| Grant number: | 18/05888-3 |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| Start date: | June 01, 2018 |
| End date: | January 31, 2023 |
| Field of knowledge: | Physical Sciences and Mathematics - Chemistry - Physical-Chemistry |
| Principal Investigator: | Wendel Andrade Alves |
| Grantee: | Barbara Bianca Gerbelli |
| Host Institution: | Centro de Ciências Naturais e Humanas (CCNH). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brazil |
| Associated research grant: | 17/02317-2 - Interfaces in materials: electronic, magnetic, structural and transport properties, AP.TEM |
| Associated scholarship(s): | 20/02192-8 - Structural investigation of lipid and amphiphilic peptides via Langmuir and Langmuir-Blodgett films, BE.EP.PD |
Abstract The main goal of the project is to develop a portable high sensitivity semiconductor transistor device for the diagnosis of human visceral leishmaniasis, a highly fatal parasitic infection, affecting mainly tropical countries. Early diagnosis is essential to prevent patient death. The chip will be based on the immobilization of synthetic peptides made from epitopes of Leishmania infantum, covalently bound into polymer gels. This will be the core of the sensitivity detection. Several complementary approaches will be used to characterize the transistors, mainly x-ray and electron microscopy, both performed in national facilities. Finally, the chips will be tested and validated through comparison with well-established diagnostic procedures (which are however time-consuming and expensive for broad use). The development of the diagnosis will involve complementary expertise from the different team members. | |
| News published in Agência FAPESP Newsletter about the scholarship: | |
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