Integrated biorefinery of agricultural wastes to obtain natural dyes and value-added bioactive compounds

• Grant number: 21/11022-1
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• Start date: April 01, 2022
• End date: March 31, 2023
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Engineering
• Principal Investigator: Maurício Ariel Rostagno
• Grantee: Leonardo Mendes de Souza Mesquita
• Supervisor: Sonia Patricia Marques Ventura
• Host Institution: Faculdade de Ciências Aplicadas (FCA). Universidade Estadual de Campinas (UNICAMP). Limeira , SP, Brazil
• Institution abroad: Universidade de Aveiro (UA), Portugal
• Associated to the scholarship: 20/08421-9 - Application of non-volatile alternative solvents to create sustainable two-dimensional and integrated platforms for harnessing agro-industrial waste from jaboticaba and pomegranate fruits, BP.PD

Abstract

Strategies for the development of a more sustainable society are the key to a promising future. The accelerated growth of the world population is directly reflected in the increase in demand for new inputs, raw materials, and food. On the other hand, food waste plagues contemporary society, generating greater social vulnerability and environmental impacts inherent to the production of this sector. In this sense, and accordance with international sustainability guidelines and the 12 principles of green chemistry, this project aims to build new platforms for the use of agro-industrial waste. In this work, we will apply biorefinery and circular economy concepts to the development of new processes for extracting bright red dyes and bioactive compounds from pomegranate and beet disposal. Alternative non-volatile solvents, namely ionic liquids and eutectic solvents, will be applied to pressurized fluid extraction (PLE). Although little explored to date, it is an efficient and biocompatible strategy, but also promising in the improvement of sustainability of extraction and purification processes. All products obtained (extracts and/or fractions) will have their production optimized, considering the reuse of solvents and the economic and environmental impacts. This project meets the proposals of the Young Researcher Project phase 2 entitled "Development of a two-dimensional system of extraction, separation and analysis for the evaluation of the bioactivity of phytochemicals." It is worth noting that this proposal will allow advancing state of the art regarding sustainable extraction and purification processes applied in waste recovery (namely in the process integration strategies for the development of new products obtained by the development of the circular economy and biorefinery concepts). With the completion of the internship, it will be possible to establish a new partnership between UNICAMP and the University of Aveiro, in addition to creating a new line of research, pioneering worldwide, to study the phenomenon inherent to PLE extraction processes associated with ionic liquids and eutectic solvents in the search for natural (stable) dyes, which seems to be a promising strategy towards the development of the green industry. (AU)

Scientific publications

(9)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

DE SOUZA MESQUITA, LEONARDO M.; CONTIERI, LETICIA S.; SOSA, FILIPE H. B.; PIZANI, RODRIGO S.; CHAVES, JAISA; VIGANO, JULIANE; VENTURA, SONIA P. M.; ROSTAGNO, MAURICIO A.. Combining eutectic solvents and pressurized liquid extraction coupled in-line with solid-phase extraction to recover, purify and stabilize anthocyanins from Brazilian berry waste. GREEN CHEMISTRY, v. 25, n. 5, p. 14-pg., 2023-02-21. (21/11022-1, 18/14582-5, 20/08421-9, 20/15774-5, 19/13496-0, 20/03623-2, 21/11023-8, 20/04067-6)

MESQUITA, LEONARDO M. DE SOUZA; CONTIERI, LETICIA S.; SANCHES, VITOR L.; KAMIKAWACHI, RENAN; SOSA, FILIPE H. B.; VILEGAS, WAGNER; ROSTAGNO, MAURICIO A.. Fast and green universal method to analyze and quantify anthocyanins in natural products by UPLC-PDA. Food Chemistry, v. 428, p. 11-pg., 2023-12-01. (21/11022-1, 18/14582-5, 20/08421-9, 19/13496-0, 20/03623-2, 21/11023-8)

MESQUITA, LEONARDO M. DE SOUZA; CONTIERI, LETICIA S.; A. E SILVA, FRANCISCA; BAGINI, RAFAEL HENRIQUE; BRAGAGNOLO, FELIPE S.; STRIEDER, MONIQUE M.; SOSA, FILIPE H. B.; SCHAEFFER, NICOLAS; FREIRE, MARA G.; VENTURA, SONIA P. M.; et al. Path2Green: introducing 12 green extraction principles and a novel metric for assessing sustainability in biomass valorization. GREEN CHEMISTRY, v. 26, n. 19, p. 21-pg., 2024-08-12. (20/15774-5, 21/11022-1, 15/00658-1, 20/08421-9, 13/04304-4, 23/12621-1, 22/10469-5, 20/03623-2, 19/13496-0, 21/11023-8, 21/12264-9, 18/14582-5, 23/05722-6)

KESHMIRSHEKAN, ABOLFAZL; MESQUITA, LEONARDO M. DE SOUZA; VENTURA, SONIA P. M.. Biocontrol manufacturing and agricultural applications of Bacilus velezensis. TRENDS IN BIOTECHNOLOGY, v. 42, n. 8, p. 16-pg., 2024-08-07. (21/11022-1, 19/13496-0, 18/14582-5, 20/08421-9)

MESQUITA, LEONARDO M. DE SOUZA; VIGANO, JULIANE; VEGGI, PRISCILLA; CONTIERI, LETICIA S.; SOSA, FILIPE H. B.; DE ROSSO, VERIDIANA VERA; VENTURA, SONIA P. M.; ROSTAGNO, MAURICIO A.. Techno-Economic analysis of an efficient anthocyanin extraction process from grape pomace using eutectic solvents ― A critical panorama regarding drying techniques and reusability of solvents. Separation and Purification Technology, v. 347, p. 9-pg., 2024-04-26. (20/15774-5, 21/11022-1, 20/08421-9, 20/03623-2, 19/13496-0, 16/18910-1, 21/11023-8, 18/14582-5)

CONTIERI, LETICIAS.; RIBEIRO, TANIA B.; SOSA, FILIPE H. B.; VAZ, BARBARA M. C.; PIZANI, RODRIGO S.; PINTADO, MANUELA; VENTURA, SONIA P. M.; MESQUITA, LEONARDO M. DE SOUZA; ROSTAGNO, MAURICIO A.. Unlocking the Full Potential of Green Propolis: A Novel Extraction Approach Using Eutectic Solvents for Improved Phenolic Compound Recovery. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 11, n. 36, p. 13-pg., 2023-08-25. (21/11022-1, 18/14582-5, 20/08421-9, 19/13496-0, 20/03623-2, 21/11023-8, 20/04067-6)

MESQUITA, LEONARDO M. DE SOUZA; CONTIERI, LETICIA S.; VAZ, BARBARA M. C.; SENCADAS, VITOR; SOSA, FILIPE H. B.; COUTINHO, JOAO A. P.; ROSTAGNO, MAURICIO A.; VENTURA, SONIA P. M.. Valorization of pomegranate waste through green solvent extraction and biochar production: a zero-waste biorefinery approach. GREEN CHEMISTRY, v. 26, n. 23, p. 18-pg., 2024-10-28. (21/11022-1, 20/08421-9, 20/03623-2, 19/13496-0, 21/11023-8, 18/14582-5)

KHOLANY, MARIAM; MACARIO, INES P. E.; VELOSO, TELMA; CONTIERI, LETICIA S.; VAZ, BARBARA M. C.; PEREIRA, JOANA L.; NUNES, CLAUDIA; COUTINHO, JOAO A. P.; ROSTAGNO, MAURICIO A.; VENTURA, SONIA P. M.; et al. Bio-based solvents as a sustainable alternative to develop a multiproduct biorefinery process from archaebacteria Halobacterium salinarum R1. GREEN CHEMISTRY, v. 26, n. 5, p. 14-pg., 2024-01-30. (21/11022-1, 20/08421-9, 20/03623-2, 19/13496-0, 21/11023-8, 18/14582-5)

DE OLIVEIRA, ISADORA LOPES; STRIEDER, MONIQUE MARTINS; BRAGAGNOLO, FELIPE SANCHEZ; SANCHES, VITOR LACERDA; MESQUITA, LEONARDO MENDES DE SOUZA; VIGANO, JULIANE; ROSTAGNO, MAURICIO ARIEL. Selective Separation of α-Punicalagin, β-Punicalagin, and Ellagic Acid from Pomegranate Husk Aqueous Extract by an Optimized Adsorption Process Employing a (Deep) Eutectic Solvent. Food and Bioprocess Technology, v. N/A, p. 12-pg., 2024-09-28. (21/11022-1, 20/08421-9, 22/10469-5, 21/12264-9, 19/13496-0, 21/13638-0, 18/14582-5, 23/05722-6)