Application of non-volatile alternative solvents to create sustainable two-dimensional and integrated platforms for harnessing agro-industrial waste from jaboticaba and pomegranate fruits

• Grant number: 20/08421-9
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Effective date (Start): February 01, 2021
• Effective date (End): January 31, 2025
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Engineering
• Principal Investigator: Maurício Ariel Rostagno
• Grantee: Leonardo Mendes de Souza Mesquita
• Host Institution: Faculdade de Ciências Aplicadas (FCA). Universidade Estadual de Campinas (UNICAMP). Limeira , SP, Brazil
• Associated research grant: 18/14582-5 - Development of a two-dimensional extraction, separation and analysis system for evaluating the bioactivity of phytochemicals, AP.JP2
• Associated scholarship(s): 21/11022-1 - Integrated biorefinery of agricultural wastes to obtain natural dyes and value-added bioactive compounds, BE.EP.PD

Abstract

Strategies for the development of a more sustainable society are crucial to a promising future. The accelerated growth of the world population reflects directly in the increased demand for new inputs, raw materials, and food. In contrast, food waste is, nowadays a huge problem, which generates social vulnerability and environmental impacts in the sector. In this sense, and in accordance with the guidelines of global sustainability goals and the 12 principles of green chemistry, the present project aims to create new platforms for the use of agroindustrial wastes. In this work, we will apply the concepts of biorefinery and circular economy for the development of new products and bioprocesses from the waste of two fruits from São Paulo agriculture (jabuticaba and pomegranate), which display an important role in the economic sector of the region. We aim to apply non-volatile alternative solvents, such as ionic liquids, eutectic solvents, and supercritical fluids, to conduct an integrative extraction and analysis of their bioactive compounds and fractions of high biological and economic value. In addition, we propose the manufacture of alternative food-packaging materials using biopolymers, in order to discourage the use of synthetic congener materials, plastic and polypropylene. All products obtained (extracts, fractions and food-packaging) will be optimized not only by their economic and environmental aspects, but also with the objective of recovering and recycling the raw materials. This project is linked to the Young Researcher Project phase 2 entitled "Development of a two-dimensional extraction, separation and analysis system for the assessment of phytochemicals bioactivity", which has the technological support for the analyzes we propose in this project. This proposal intends to improve the state-of-the-art by unifying the sustainability of solvents and processes towards the recovery of wastes (integrated systems and alternative solvents). Therefore, with the implementation of this proposal, it will be possible to generate new strategies for the development of a more sustainable and economically active society.

Publicações científicas

(13)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

CHAVES, JAISA O.; SANCHES, VITOR L.; VIGANO, JULIANE; MESQUITA, LEONARDO M. DE SOUZA; DE SOUZA, MARIANA C.; DA SILVA, LAISE C.; ACUNHA, TANIZE; FACCIOLI, LUCIA H.; ROSTAGNO, MAURICIO A.. Integration of pressurized liquid extraction and in-line solid-phase extraction to simultaneously extract and concentrate phenolic compounds from lemon peel (Citrus limon L.). Food Research International, v. 157, p. 12-pg., 2022-07-01. (13/04304-4, 20/08421-9, 15/00658-1, 19/13496-0, 18/14582-5, 20/15774-5)

VIGANO, JULIANE; STRIEDER, MONIQUE MARTINS; PIZANI, RODRIGO S.; CONTIERI, LETICIA S.; MESQUITA, LEONARDO M. DE SOUZA; ROSTAGNO, MAURICIO A.. Application of an integrative system (2D PLExHPLC-PDA) for bioactive compound extraction and online quantification: Advantages, validation, and considerations. Analytica Chimica Acta, v. 1272, p. 9-pg., 2023-06-15. (18/14582-5, 20/08421-9, 20/15774-5, 19/13496-0, 21/12264-9, 20/03623-2, 20/04067-6)

DE SOUZA MESQUITA, LEONARDO M.; CONTIERI, LETICIA S.; SOSA, FILIPE H. B.; PIZANI, RODRIGO S.; CHAVES, JAISA; VIGANO, JULIANE; VENTURA, SONIA P. M.; ROSTAGNO, MAURICIO A.. Combining eutectic solvents and pressurized liquid extraction coupled in-line with solid-phase extraction to recover, purify and stabilize anthocyanins from Brazilian berry waste. GREEN CHEMISTRY, v. 25, n. 5, p. 14-pg., 2023-02-21. (21/11022-1, 18/14582-5, 20/08421-9, 20/15774-5, 19/13496-0, 20/03623-2, 21/11023-8, 20/04067-6)

SANCHES, VITOR L.; DE SOUZA MESQUITA, LEONARDO M.; VIGANO, JULIANE; CONTIERI, LETICIA S.; PIZANI, RODRIGO; CHAVES, JAISA; DA SILVA, LAISE CAPELASSO; DE SOUZA, MARIANA CORREA; BREITKREITZ, MARCIA CRISTINA; ROSTAGNO, MAURICIO A.. Insights on the Extraction and Analysis of Phenolic Compounds from Citrus Fruits: Green Perspectives and Current Status. CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, v. N/A, p. 27-pg., 2022-08-16. (18/14582-5, 20/15774-5, 19/13496-0, 19/24537-0, 20/08421-9, 20/03623-2)

MESQUITA, LEONARDO M. DE SOUZA; CONTIERI, LETICIA S.; SANCHES, VITOR L.; KAMIKAWACHI, RENAN; SOSA, FILIPE H. B.; VILEGAS, WAGNER; ROSTAGNO, MAURICIO A.. Fast and green universal method to analyze and quantify anthocyanins in natural products by UPLC-PDA. Food Chemistry, v. 428, p. 11-pg., 2023-12-01. (21/11022-1, 18/14582-5, 20/08421-9, 19/13496-0, 20/03623-2, 21/11023-8)

CONTIERI, LETICIA S.; MESQUITA, LEONARDO M. DE SOUZA; SANCHES, VITOR L.; VIGANO, JULIANE; KAMIKAWACHI, RENAN CANUTE; VILEGAS, WAGNER; ROSTAGNO, MAURICIO A.. Ultra-high-performance liquid chromatography using a fused-core particle column for fast analysis of propolis phenolic compounds. JOURNAL OF SEPARATION SCIENCE, v. 46, n. 3, p. 12-pg., 2022-12-09. (18/14582-5, 19/13496-0, 20/08421-9, 20/15774-5)

VIGANO, JULIANE; SANCHES, VITOR L.; MESQUITA, LEONARDO M. DE SOUZA; DE SOUZA, MARIANA C.; DA SILVA, LAISE C.; CHAVES, JAISA O.; FORSTER-CARNEIRO, TANIA; ROSTAGNO, MAURICIO A.. Comprehensive analysis of phenolic compounds from natural products: Integrating sample preparation and analysis. Analytica Chimica Acta, v. 1178, SEP 15 2021. (19/24537-0, 18/14582-5, 19/18772-6, 20/08421-9, 18/17089-8, 13/04304-4, 18/14938-4, 20/15774-5)

DA SILVA, LAISE C.; VIGANO, JULIANE; DE SOUZA MESQUITA, LEONARDO M.; BAIAO DIAS, ARTHUR L.; DE SOUZA, MARIANA C.; SANCHES, VITOR L.; CHAVES, JAISA O.; PIZANI, RODRIGO S.; CONTIERI, LETICIA S.; ROSTAGNO, MAURICIO A.. Recent advances and trends in extraction techniques to recover polyphenols compounds from apple by-products. FOOD CHEMISTRY-X, v. 12, DEC 30 2021. (20/08421-9, 20/03623-2, 19/24537-0, 20/15774-5, 19/18772-6, 19/13496-0, 18/17089-8, 20/04067-6, 18/14582-5)

CONTIERI, LETICIA S.; MESQUITA, LEONARDO M. DE SOUZA; SANCHES, VITOR L.; CHAVES, JAISA; PIZANI, RODRIGO S.; DA SILVA, LAISE C.; VIGANO, JULIANE; VENTURA, SONIA P. M.; ROSTAGNO, MAURICIO A.. Recent progress on the recovery of bioactive compounds obtained from propolis as a natural resource: Processes, and applications. Separation and Purification Technology, v. 298, p. 18-pg., 2022-07-06. (18/17089-8, 19/18772-6, 18/14582-5, 20/08421-9, 19/24537-0, 20/15774-5, 20/03623-2, 20/04067-6)

PIZANI, RODRIGO S.; VIGANO, JULIANE; DE SOUZA MESQUITA, LEONARDO M.; CONTIERI, LETICIA S.; SANCHES, VITOR L.; CHAVES, JAISA O.; SOUZA, MARIANA C.; DA SILVA, LAISE C.; ROSTAGNO, MAURICIO A.. Beyond aroma: A review on advanced extraction processes from rosemary (Rosmarinus officinalis) and sage (Salvia officinalis) to produce phenolic acids and diterpenes. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 127, p. 18-pg., 2022-08-02. (18/17089-8, 18/14582-5, 20/08421-9, 19/24537-0, 20/15774-5, 20/03623-2, 19/13496-0, 20/04067-6)

SANCHES, VITOR L.; CUNHA, TANIZE A.; VIGANO, JULIANE; DE SOUZA MESQUITA, LEONARDO M.; FACCIOLI, LUCIA HELENA; BREITKREITZ, MARCIA CRISTINA; ROSTAGNO, MAURICIO A.. Comprehensive analysis of phenolics compounds in citrus fruits peels by UPLC-PDA and UPLC-Q/TOF MS using a fused-core column. FOOD CHEMISTRY-X, v. 14, p. 9-pg., 2022-02-22. (20/08421-9, 19/13496-0, 18/14582-5, 20/15774-5)

CONTIERI, LETICIA S.; DE SOUZA MESQUITA, LEONARDO M.; SANCHES, VITOR L.; VIGANO, JULIANE; MARTINEZ, JULIAN; DA CUNHA, DIOGO T.; ROSTAGNO, MAURICIO A.. Standardization proposal to quality control of propolis extracts commercialized in Brazil : A fingerprinting methodology using a UHPLC-PDA-MS/MS approach. Food Research International, v. 161, p. 11-pg., 2022-08-30. (18/14582-5, 19/13496-0, 20/08421-9, 20/03623-2, 20/15774-5)

CONTIERI, LETICIAS.; RIBEIRO, TANIA B.; SOSA, FILIPE H. B.; VAZ, BARBARA M. C.; PIZANI, RODRIGO S.; PINTADO, MANUELA; VENTURA, SONIA P. M.; MESQUITA, LEONARDO M. DE SOUZA; ROSTAGNO, MAURICIO A.. Unlocking the Full Potential of Green Propolis: A Novel Extraction Approach Using Eutectic Solvents for Improved Phenolic Compound Recovery. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 11, n. 36, p. 13-pg., 2023-08-25. (21/11022-1, 18/14582-5, 20/08421-9, 19/13496-0, 20/03623-2, 21/11023-8, 20/04067-6)