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Development and application of methods for the green and sustainable extraction of bioactive phenolic compounds derived from mango waste

Grant number: 19/08389-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): July 01, 2019
Effective date (End): December 31, 2019
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Principal Investigator:Vânia Gomes Zuin Zeidler
Grantee:Karine Zanotti
Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil


The magnitude of Brazilian agro-industrial production causes concern about the amount of waste generated. These have important properties, beneficial to human health, which can be exploited in integrated chemical platforms, the biorefineries. Mango (Mangifera indica L.) is produced on a large scale in Brazil and traditionally processed in manufactured products, whose residues are not yet properly utilized. Thus, this project has as main objective to develop, optimize and apply methods to extract bioactive compounds, such as mangiferin and hyperoside, from mango waste produced in the state of São Paulo, considering the principles of Green Analytical Chemistry. Using chemometrics for the planning of experiments, different extraction methods considered greener and more sustainable, like the based on solid phase matrix dispersion (MSPD) and the microwave (MAE), will be tested and analyzed, and the analytes will be determined by liquid chromatography (UPLC) coupled to the PDA/UV-Vis detector. In addition to the best analytical parameters, it will be possible to compare which extraction techniques are greener, using specific metrics for this purpose.

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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ZUIN, VANIA G.; RAMIN, LUIZE Z.; SEGATTO, MATEUS L.; STAHL, AYLON M.; ZANOTTI, KARINE; FORIM, MOACIR R.; DA SILVA, MARIA FATIMA DAS GRACAS F.; FERNANDES, JOAO BATISTA. To separate or not to separate: what is necessary and enough for a green and sustainable extraction of bioactive compounds from Brazilian citrus waste. Pure and Applied Chemistry, v. 93, n. 1, p. 13-27, . (12/25299-6, 19/08389-0, 14/50827-1, 18/11409-0, 17/25015-1)
ZUIN, VANIA G.; STAHL, AYLON M.; ZANOTTI, KARINE; SEGATTO, MATEUS L.. Green and sustainable chemistry in Latin America: Which type of research is going on? And for what?. CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY, v. 25, p. 8-pg., . (14/50827-1, 18/11409-0, 17/25015-1, 19/08389-0)
SEGATTO, MATEUS LODI; STAHL, AYLON MATHEUS; ZANOTTI, KARINE; ZUIN, VANIA GOMES. Green and sustainable extraction of proteins from agro-industrial waste: An overview and a closer look to Latin America. CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY, v. 37, p. 7-pg., . (18/11409-0, 17/25015-1, 19/08389-0)

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