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Molar Incisor Hypomineralization (MIH): relevant outcomes in epidemiological survey and parents preferences regarding treatment

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Author(s):
Fernanda Lyrio Mendonça
Total Authors: 1
Document type: Doctoral Thesis
Press: Bauru.
Institution: Universidade de São Paulo (USP). Faculdade de Odontologia de Bauru (FOB/SDB)
Defense date:
Examining board members:
Daniela Rios Honório; Juliana Feltrin de Souza Caparroz; Marina de Deus Moura de Lima; Linda Wang
Advisor: Daniela Rios Honório
Abstract

Article 1 evaluated the association between Molar Incisor Hypomineralization (MIH) and Hypomineralized Second Primary Molars (HSPM) in 680 schoolchildren. Data were analyzed using descriptive analysis and logistic regression model (LRM). Among the evaluated children, 4.3% had HSPM and MIH. The LRM showed that sex and HSPM impacted the occurrence of MIH. Children with HSPM were 2.9 times more likely to have MIH than those without HSPM. Article 2 compared different MIH diagnostic indices the simplified/MIH_s and extended/MIH_e MIH index and the MIHSeverity Scoring System/MIH-SSS in 680 schoolchildren. The prevalence of MIH was 24.7% and the most common clinical feature was demarcated opacity (81.7%-MIH_s and 85.45%-MIH-SSS). A positive association was observed between the indices (chisquare test). MIH-SSS demonstrated a shorter average application time compared to MIH_s and MIH_e (ANOVA/Tukey). All indexes effectively diagnosed MIH and its characteristics. Article 3 evaluated whether the occurrence of post-eruptive breakdown (PEB), atypical restoration and atypical caries is influenced by the opacity color of the MIH-affected tooth. Data were analyzed using descriptive analysis and chi-square test. The occurrence of yellow-brown demarcated opacity was 63.29% and its presence influenced the occurrence of PEB, atypical restoration and atypical caries. Article 4 assessed whether the number of teeth affected by MIH, severity of MIH, previous caries experience, visible plaque index (VPI), gingival bleeding index (ISG), age and sex impact the development of caries in first permanent molars. Schoolchildren (n=476) were evaluated for the diagnosis of MIH, caries lesions, VPI and ISG. Zeroinflated negative binomial regression was used to evaluate the impact of variables on the development of caries lesions, considering or not the atypical restoration of molars with MIH. In the presence of restoration, age, severity of MIH and previous caries experience significantly impacted the development of caries lesions (R2=0.176). Without atypical restoration in molars affected by MIH, only age and previous caries experience were statistically significant (R2=0.167). MIH did not influence the presence of caries lesions in molars with MIH. Article 5 assessed parents\' knowledge and preferences regarding different treatments for MIH. Parents (n=50) answered a knowledge questionnaire about MIH before and after viewing an explanatory video, followed by a questionnaire with different clinical situations and treatment options. Data were analyzed using descriptive analysis and the Wilcoxon test. An increase in the level of knowledge and confidence was observed after watching the video. For molars, parental choices were different in scenarios with the presence of pain compared to scenarios without pain. For incisors, it was noted that parents opted for a more invasive approach in the presence of pain and aesthetic complaints. (AU)

FAPESP's process: 19/02735-4 - Molar incisor hypomineralization: prevalence, clinical performance of new materials for the treatment of hypersensibility and parent's perception in relation to the possibilities of treatment
Grantee:Fernanda Lyrio Mendonça
Support Opportunities: Scholarships in Brazil - Doctorate