CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Professor in the Federal University of São Paulo (Unifesp) at Diadema (São Paulo, Brazil). Bachelor (1998), Master (1998) and Ph.D. (2005) Degree in Chemistry (Physical Chemistry) from University of São Paulo (USP) at Ribeirão Preto. Post-Doc researcher (2005-2008) at the Physics Institute of São Carlos (USP). Internship in the University of Miami, USA, (2004), National University of Cordoba, Argentina, (2003) and Biolin, Finland (2007).Expert in Langmuir and Langmuir-Blodgett films and their applications as nanomaterials and biomembrane models. (Source: Lattes Curriculum)
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We propose the Brazilian team deliver a seminar/short course about nanotechnology at the University of Antioquia. We believe that this would impact in the following terms: i) Stimulate future exchange students from Colombia to go to Brazil in future partnership programs; ii) Establish closer collaboration with other Prof. Giordani's collaborators at Antioquia University; and iii) Discuss …
In this project, we intend to use Langmuir and Langmuir-Blodgett (LB) films with two main objectives: (i) interaction studies of bioactive compounds in biointerface models, including cell membranes, viral envelopes, alveolar membranes, and supramolecular lipoprotein systems, and (ii) for the immobilization of enzymes, carbonaceous materials, and conductive polymers in ultra-thin nanostruc…
In this project, we intend to use structures organized at the molecular level at interfaces as cell membrane models, and for the immobilization of enzymes for the production of enzymatic optoelectronic devices. For that, we will use Langmuir monolayers and Langmuir-Blodgett (LB) films. The films will be produced from materials of pharmacological and / or technological interest, in which i…
(Only some records are available in English at this moment)
In this project, we intend to study the uridine derivative, 3',4'-acetonide-uridine-succinate-cholesterol (PNM3), which has anticancer drug potential, in membrane models using Langmuir and Langmuir-Blodgett (LB) films of lipids, and complemented with studies on liposomes and through molecular simulation. The lipids to be used will be those found in cell membranes (phosphatidylcholines, ph…
In this project, we intend to study the action of mirsinoic acid, a compound with potential antimicrobial and antitumor activity, with Langmuir films of phospholipids, which will serve as cell membrane models. The phospholipids to be used will be dipalmitoylphosphatidyl phosphatidylcholine (DPPC) and dipalmitoyl phosphatidyl serine (DPPS), which will be co-spread with the bioactive. The i…
In this work we intend to study the interaction of the laccase enzyme in Langmuir and Langmuir-Blodgett (LB) films of dimyristoylphosphatidic acid/graphene oxide. The lipid will be spread at the air-water interface and the enzyme, as well as graphene oxide dispersions, will be inserted into the supporting aqueous subphase of the lipid monolayer. The adsorption of the enzyme to the monolay…
(Only some records are available in English at this moment)
The interaction between the SARS-CoV-2 envelope and host cell membrane is central to viral infection. One strategy to investigate this interaction involves using models that partially replicate these structures, enabling the extraction of difficult molecular information about the natural system. This project aims to employ liposomes (large unilamellar vesicles, LUVs) to mimic the SARS-CoV…
In this project, we intend to study the interaction of lisycamine, an aporphinoid alkaloid found in plants of the family Annonaceae, which has leishmanicidal and antitumor activities, with cell membrane models. From the thermodynamic, electrical, morphological, rheological and spectroscopic characterization of the models, we aimed to understand at the molecular level the interactions of t…
In this project, we intend to study the action of vancomycin with Langmuir films of phospholipids, which serve as simple models of cell membranes. The phospholipids to be used will be dipalmitoyl phosphatidylcholine (DPPC) and dipalmitoyl phosphatidyl ethanolamine (DPPE), co-mixed with the bioactive. The interaction of vancomycin with the phospholipid monolayers will be evaluated by means…
(Only some records are available in English at this moment)
This project aims to investigate the interaction of 3,4-acetonide-uridine-succinate-cholesterol (PNM3), a compound with recognized anticancer potential, with model membranes using Langmuir monolayers composed of lipid mixtures. The selected phospholipids will reflect those abundant in cellular membranes, including phospholipids with choline, ethanolamine, or serine as polar headgroups, al…
The interaction between the SARS-CoV-2 envelope and the host cell membrane is central to viral infection. The first step in the virus's entry into cells involves the binding of the receptor-binding domain (RBD), a part of the SARS-CoV-2 Spike protein, to the cellular receptor angiotensin-converting enzyme 2 (ACE2). Due to the complexity of this biological process, one strategy to investig…
In this project, we aim to develop a biosensor for the detection and quantification of phenolic compounds using Langmuir and Langmuir-Blodgett films composed of 1,2-dimyristoyl-sn-glycero-3-phosphate (sodium salt), the conductive polymer poly(3-hexylthiophene-2,5-diyl) (P3HT), graphene oxide, and the enzyme laccase. This approach will allow us to explore the physicochemical properties of …
This project aims to investigate the adsorption of mucins, crucial surface glycoproteins found on protozoan membranes, into Langmuir monolayers composed of DPPE (dipalmitoylphosphatidylethanolamine) and POPE (palmitoyl oleoyl phosphoethanolamine). Additionally, we will explore the interaction between antiprotozoal acetogenins and these hybrid protein-lipid monolayer systems, as well as go…
In this Project, we intend to create a biosensor that detects and quantifies phenol compounds, utilizing Langmuir and Langmuir-Blodgett films of lipids (octadecylamine, cholesterol) and the conductive polymer Poly(3-hexylthiophene-2,5-diyl) (P3HT) with the enzyme laccase and carbon nanotubes functionalized with octadecylamine (CNT-ODA). This technique could allow us to investigate the phy…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 10 / 9 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 19 / 14 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 4 / 4 | Completed scholarships abroad |
| 41 / 35 | All research grants and scholarships |
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