CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Chemistry from Universidade de Brasília (1996). Master's at Chemistry from Universidade de São Paulo (1999), PhD at Analytical Chemistry from Universidade de São Paulo (2003). Has experience in Toxicology of metals and Atomic spectrometry applied to clinical sample analysis. (Source: Lattes Curriculum)
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The Brazilian Amazon, spanning approximately 9 million km², harbors one of the greatest biological and sociocultural diversities on Earth. However, the region has been historically affected by extractive and artisanal mining activities, contributing to both environmental degradation and human exposure to toxic substances, particularly heavy metals such as lead (Pb). Lead is highly toxic e…
Environmental hazards account for a large, but not well characterized, proportion of the burden of disease. The exposome, described as "the totality of human environmental exposures from conception onwards", recognizes that individuals are exposed simultaneously to a multitude of different environmental factors and takes a holistic approach to the discovery of etiological factors for dise…
The overall impact of mercury (Hg) pollution is indisputable (Minamata convention on Hg), and some populations are recognized as particularly vulnerable and at high risk. The Brazilian Amazon is one of the regions most affected by Hg in the world. In this area, Hg can be released into aquatic ecosystems by anthropogenic (mainly through gold mining) and natural (such as soil leaching) proc…
(Only some records are available in English at this moment)
Mercury pollution, a severe issue globally and particularly in the Brazilian Amazon due to activities like gold mining and deforestation, poses serious health risks to local communities. High Hg exposure levels have been documented in these populations, leading to concerns about neurological impacts and other health effects resembling Minamata disease. Interestingly, despite elevated Hg l…
Mercury (Hg) pollution has a well-known impact, highlighted by the Minamata Convention on Hg. Certain populations are especially vulnerable and at high risk. The Brazilian Amazon is one of the regions most affected by mercury pollution globally. Here, mercury enters aquatic ecosystems through human activities, primarily gold mining, and natural processes like soil leaching. This leads to …
The hydroelectric power plants (HPP) are one of the largest economic resources in the Amazon that, however, can disproportionately impact traditional communities such as the riverines communities. Pará is home to the fifth largest HPP in the world, the HPP Tucuruí, constituting a unique model for generating data that can support actions to minimize the impact on the most vulnerable popula…
(Only some records are available in English at this moment)
Riverine populations of the Amazon are chronically exposed to toxic metals such as mercury (Hg), lead (Pb), arsenic (As), and cadmium (Cd), primarily through their traditional diet, which is rich in fish and locally grown products. This exposure poses a threat to genomic integrity and may contribute to accelerated cellular aging. Telomeres-repetitive DNA regions located at the ends of chr…
The dietary and lifestyle habits of riverside communities in the Amazon can pose significant risks to individual health. One example is the high consumption of fish - the main source of animal protein for these populations - which results in chronic exposure to high concentrations of mercury (Hg). In addition, the presence of lead (Pb) has been identified in cassava flour, a widely consum…
The riverside populations of the Amazon face chronic exposure to toxic metals, such as mercury (Hg) and lead (Pb), primarily due to the consumption of fish and manioc flour. This exposure poses a serious health risk and is associated with adverse neurological, renal, and cardiovascular effects. Evidence suggests that selenium (Se) may act as a protective factor against the toxicity of the…
(Only some records are available in English at this moment)
The Amazon riverside population is unique, considering its geographic location, culture, and lifestyle. Another specific characteristic of this population is the high selenium (Se) and other compounds concentration in blood, such as methylmercury (MeHg), without signs and symptoms of intoxication. Some previous studies formulated hypotheses about the mechanisms associated with the absence…
(Only some records are available in English at this moment)
The expansion of industrial and agricultural activities has increased human exposure to many toxic substances. After exposure, most of these chemicals can interact with the human organism, leading to a higher predisposition to specific pathologies. Among these chemicals, the aromatic amines (AAs) are a class of emerging pollutants often used as by-products in manufacturing dyes, textiles,…
Bisphenols are endocrine disruptors commonly used in the manufacture of plastic products and extensively studied regarding their potential adverse effects on the endocrine system and organs that are subject to endocrine regulation. In the last decades, many scientific reports showed that bisphenol A (BPA), an endocrine disruptor, can adversely affect energy metabolism, leading to impairme…
Engineered nanoparticles especially the gold nanoparticles (AuNPs) are widely used in various biomedical applications such as drug delivery, cancer treatment, biomedical imaging, diagnosis etc. To a large extent, their reported low toxicity to mammals seems to be one of the important features that make them to be desired in such applications. Most toxicological, uptake and biodistribution…
(Only some records are available in English at this moment)