Challenges and perspectives to enhance cattle production via in vitro techniques: focus on epigenetics and cell-secreted vesicles

Author(s)

Bressan, Fabiana Fernandes ^{[1, 2]} ; Fantinato-Neto, Paulo ^{[3, 2]} ; Andrade, Gabriella Mamede ^[1] ; Sangalli, Juliano Rodrigues ^{[1, 2]} ; Sampaio, Rafael Vilar ^{[1, 2]} ; da Silveira, Juliano Coelho ^[1] ; Perecin, Felipe ^{[1, 2]} ; Meirelles, Flavio Vieira ^{[1, 2]}

Affiliation

^[1] Univ Sao Paulo, FZEA, Dept Vet Med, BR-13635000 Pirassununga, SP - Brazil

^[2] Univ Sao Paulo, FMVZ, Dept Cirurgia, BR-09500900 Sao Paulo, SP - Brazil

^[3] Ctr Univ Moura Lacerda, Ribeirao Preto, SP - Brazil

• Document type: Journal article
• Source: Ciência Rural; v. 45, n. 10, p. 1879-1886, OCT 2015.
• Web of Science Citations: 1

Abstract

This review aim to present some clinical problems found in IVP-derived animals focusing on NT procedures and to discuss the possible role of epigenetics in such process. Also, as cell-secreted vesicles have been reported as possible regulators of important physiological reproductive processes such as folliculogenesis and fertilization, it is also presented herein a new perspective of manipulating the pre-implantation period trough effector molecules contained in such vesicles. (AU)

• FAPESP's process: 08/57877-3 - National Institute of Science and Technology in Cell Therapy
• Grantee: Roberto Passetto Falcão
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 13/08135-2 - CTC - Center for Cell-Based Therapy
• Grantee: Dimas Tadeu Covas
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• FAPESP's process: 14/21034-3 - Intra and intercellular routes during foliculogenesis and in vivo and in vitro oocyte maturation
• Grantee: Felipe Perecin
• Support Opportunities: Regular Research Grants