Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of 4-(N,N-dimethylamino)phenethyl Alcohol on Degree of Conversion and Cytotoxicity of Photo-Polymerized CQ-Based Resin Composites

Full text
Author(s):
Dayane Carvalho Ramos Salles de Oliveira [1] ; Camila Batista da Silva [2] ; Bruno Vilela Muniz [3] ; Maria C. Volpato [4] ; Ana Rosa Costa [5] ; Mario Alexandre Coelho Sinhoreti [6]
Total Authors: 6
Affiliation:
[1] UNICAMP - University of Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[2] UNICAMP - University of Campinas. Piracicaba Dental School. Department of Physiological Sciences - Brasil
[3] UNICAMP - University of Campinas. Piracicaba Dental School. Department of Physiological Sciences - Brasil
[4] UNICAMP - University of Campinas. Piracicaba Dental School. Department of Physiological Sciences - Brasil
[5] UNICAMP - University of Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[6] UNICAMP - University of Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Brazilian Dental Journal; v. 25, n. 6, p. 538-542, 2014-12-00.
Abstract

The aim of this study was to evaluate the degree of conversion (DC) and the cytotoxicity of photo-cured experimental resin composites containing 4-(N,N-dimethylamino)phenethyl alcohol (DMPOH) combined to the camphorquinone (CQ) compared with ethylamine benzoate (EDAB). The resin composites were mechanically blended using 35 wt% of an organic matrix and 65 wt% of filler loading. To this matrix was added 0.2 wt% of CQ and 0.2 wt% of one of the reducing agents tested. 5x1 mm samples (n=5) were previously submitted to DC measurement and then pre-immersed in complete culture medium without 10% (v/v) bovine serum for 1 h or 24 h at 37 °C in a humidifier incubator with 5% CO2 and 95% humidity to evaluate the cytotoxic effects of experimental resin composites using the MTT assay on immortalized human keratinocytes cells. As a result of absence of normal distribution, the statistical analysis was performed using the nonparametric Kruskal-Wallis to evaluate the cytotoxicity and one-way analysis of variance to evaluate the DC. For multiple comparisons, cytotoxicity statistical analyses were submitted to Student-Newman-Keuls and DC analysis to Tukey's HSD post-hoc test (=0.05). No significant differences were found between the DC of DMPOH (49.9%) and EDAB (50.7%). 1 h outcomes showed no significant difference of the cell viability between EDAB (99.26%), DMPOH (94.85%) and the control group (100%). After 24 h no significant difference were found between EDAB (48.44%) and DMPOH (38.06%), but significant difference was found compared with the control group (p>0.05). DMPOH presented similar DC and cytotoxicity compared with EDAB when associated with CQ. (AU)

FAPESP's process: 13/04241-2 - The influence of the photoinitiator system and reducing agents on physical properties of experimental resins photoactivated by LEDs
Grantee:Dayane Carvalho Ramos Salles de Oliveira
Support Opportunities: Scholarships in Brazil - Doctorate