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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Solubility of protocatechuic acid, sinapic acid and chrysin in supercritical carbon dioxide

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Author(s):
Paula, Julia T. [1] ; Sousa, Ilza M. O. [2] ; Foglio, Mary A. [3] ; Cabral, Fernando A. [1]
Total Authors: 4
Affiliation:
[1] State Univ Campinas UNICAMP, Dept Food Engn, BR-13083862 Campinas, SP - Brazil
[2] State Univ Campinas UNICAMP, Chem Biol & Agr Pluridisciplinary Res Ctr CPQBA, BR-13083970 Campinas, SP - Brazil
[3] State Univ Campinas UNICAMP, Fac Pharmaceut Sci, BR-13081970 Campinas, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: JOURNAL OF SUPERCRITICAL FLUIDS; v. 112, p. 89-94, JUN 2016.
Web of Science Citations: 10
Abstract

Solubility data of some phenolic compounds of industrial interest, such as protocatechuic acid (3,4-dihydroxybenzoic acid), chrysin (5,7-dihydroxyflavone) and sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) in supercritical carbon dioxide were determined at pressures of 200, 300 and 400 bar and temperatures of 40, 50 and 60 degrees C. Experimental data were correlated with semi-empirical Chrastil model and thermodynamic modeling using the Peng-Robinson equation of state with classical mixing rule. The critical properties, acentric factor, and vapor pressure of these compounds were estimated by group contribution methods. The solubility values followed a similar tendency, with higher solubility with increasing temperature and pressure, and no crossover pressure in the range studied. However, a crossover pressure around 150 bar was observed when extrapolating the solubility data by the Chrastil equation, which is in agreement with values reported in the literature for phenolic compounds, thereby indicating the consistency of the solubility experimental data. (C) 2016 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 12/51317-1 - Development of products and processes with supercritical technology: construction of one multipurpose unit to obtain extracts of industrial interest.
Grantee:Fernando Antonio Cabral
Support Opportunities: Regular Research Grants