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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents

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Author(s):
William Marciel de Souza ; Alex Martins Machado ; Luiz Tadeu Moraes Figueiredo
Total Authors: 3
Document type: Journal article
Source: Memórias do Instituto Oswaldo Cruz; v. 111, n. 6, p. 399-402, Jun. 2016.
Web of Science Citations: 1
Abstract

This study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals. (AU)

FAPESP's process: 11/05067-0 - Study of the mechanisms of infection and transmission of hantaviruses in rodent reservoir Araraquara (Necromys lasiurus)
Grantee:William Marciel de Souza
Support type: Scholarships in Brazil - Master
FAPESP's process: 12/24150-9 - Research of virus in wild rodents, mosquitoes and ticks
Grantee:William Marciel de Souza
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 09/17518-7 - Characterization of Araraquara hantavirus infection in natural reservoirs (Necromys lasiurus) and in rodent model of human disease (Mesocricetus auratus)
Grantee:Alex Martins Machado
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 08/50617-6 - Studies on emerging viruses including arbovirus, robovirus, respiratory viruses and congenital transmission, at the Centro de Pesquisa em Virologia da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo
Grantee:Luiz Tadeu Moraes Figueiredo
Support type: Research Projects - Thematic Grants