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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evaluation and characterization of plasmids carrying CTX-M genes in a non-clonal population of multidrug-resistant Enterobacteriaceae isolated from poultry in Brazil

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Author(s):
Ferreira, Joseane Cristina ; Casarin Penha Filho, Rafael Antonio ; Andrade, Leonardo Neves ; Berchieri Junior, Angelo ; Costa Darini, Ana Lucia
Total Authors: 5
Document type: Journal article
Source: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE; v. 85, n. 4, p. 444-448, AUG 2016.
Web of Science Citations: 11
Abstract

The increasing presence of ESBL-producing bacteria in food-producing animals might impact on public health. In this study, ESBL-producing enterobacteria were investigated in the microbiota of chickens produced in Brazil. We detected bla(CTX-M-2), bla(CTX-M-8) and bla(CTX-M-15) in 13 Escherichia coli isolates, within 9 different PFGE-types. Escherichia fergusonii and Klebsiella pneumoniae were found carrying bla(CTX-M-2). Plasmid Inc groups found included repF, FIB, FIC, I1, Y, B/O, A/C, K and HI1. F plasmids were present in 87.5% of the isolates, however, no resistance gene was harbored in this replicon. The pMLST for IncI1 showed ST113 and the novel ST130, ST131 and ST132 harboring bla(CTX-M-8). IncK plasmids carried bla(CTX-M-2) in one E. coli isolate. Non-typeable plasmids carrying bla(CTX-M-2) or bla(CTX-M-15) had up to 260 kb. bla(CTX-M-2) was also associated with class I integron and ISCR1 and bla(CTX-M-8) with IS10. Overall, similar resistance elements were disseminated among a diverse population of ESBL-producing enterobacteria. (C) 2016 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 11/08892-2 - Molecular investigation of Klebsiella pneumoniae strains and plasmids carring beta-lactamases encoding genes
Grantee:Leonardo Neves de Andrade
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 12/24017-7 - Evaluation of the infection and immunity in susceptible and resistant lines of chickens (Gallus Gallus) challenged with Salmonella enterica subsp. enterica serovar Gallinarum
Grantee:Rafael Antonio Casarin Penha Filho
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 14/14494-8 - Molecular epidemiology of gram-negative bacteria and genetic of antibiotic resistance
Grantee:Ana Lúcia da Costa Darini
Support type: Research Projects - Thematic Grants