| Full text | |
| Author(s): |
Mazarin de Moraes, Ana Carolina
;
Kubota, Lauro Tatsuo
Total Authors: 2
|
| Document type: | Review article |
| Source: | CHEMOSENSORS; v. 4, n. 4 DEC 2016. |
| Web of Science Citations: | 20 |
| Abstract | |
Immunosensors are analytical platforms that detect specific antigen-antibody interactions and play an important role in a wide range of applications in biomedical clinical diagnosis, food safety, and monitoring contaminants in the environment. Field-effect transistors (FET) immunosensors have been developed as promising alternatives to conventional immunoassays, which require complicated processes and long-time data acquisition. The electrical signal of FET-based immunosensors is generated as a result of the antigen-antibody conjugation. FET biosensors present real-time and rapid response, require small sample volume, and exhibit higher sensitivity and selectivity. This review brings an overview on the recent literature of FET-based immunosensors, highlighting a diversity of nanomaterials modified with specific receptors as immunosensing platforms for the ultrasensitive detection of various biomolecules. (AU) | |
| FAPESP's process: | 13/22127-2 - Development of novel materials strategic for integrated analytical devices |
| Grantee: | Lauro Tatsuo Kubota |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 16/04739-9 - Fabrication of fieldeffect transistors (FET) immunosensors based on chemically modified graphenes for the ultrasensitive detection of lung cancer biomarkers |
| Grantee: | Ana Carolina Mazarin de Moraes |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |