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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Do metabolic syndrome and its components have an impact on bone mineral density in adolescents?

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da Silva, Valeria Nobrega ; Mosca Fiorelli, Luciana Nunes ; da Silva, Carla Cristiane ; Kurokawa, Cilmery Suemi ; Lederer Goldberg, Tamara Beres
Total Authors: 5
Document type: Review article
Source: NUTRITION & METABOLISM; v. 14, JAN 4 2017.
Web of Science Citations: 9

In recent years, there has been growing concern about the occurrence of metabolic syndrome (MetS) at an early age and its effects on bone mass in adolescents. Adolescence is considered a critical period for bone mass gain. Impaired bone acquisition during this phase can lead to ``suboptimal{''} peak bone mass and increase the risk of osteopenia/osteoporosis and fractures in old age. The objective of this review was to perform a critical analysis of articles that specifically focus on this age group, evaluating the influence of MetS and its components on bone mineral density in adolescents. A possible relationship between this syndrome and bone mass has been demonstrated, but the number of studies addressing this topic in adolescents is small. Despite the scarcity of evidence, the results of those studies show that Metabolic Syndrome is negatively correlated with bone mass and also that some components of MetS are negatively correlated with bone mineral density in adolescents. However, the associations between MetS and bone mass development need to be further explored in the age group corresponding to adolescence. Further good-quality studies are necessary to complement the understanding of this relationship. (AU)

FAPESP's process: 11/05991-0 - The impact of body fat excess on bone densitometry and bone metabolims biomarkers: a study with overweight, obese and superobese adolescents
Grantee:Tamara Beres Lederer Goldberg
Support type: Regular Research Grants
FAPESP's process: 15/04040-2 - Bone mineral density and bone biomarkers assessment in adolescents user of low-dose combined oral contraceptive (ethinylestradiol 20µg/Desogestrel 150µg): 1 year follow-up
Grantee:Tamara Beres Lederer Goldberg
Support type: Regular Research Grants
FAPESP's process: 07/07731-0 - Bone mineral density and content in healthy female adolescents between 10 and 20 years old and their relationship with bone formation and reabsorption markers
Grantee:Tamara Beres Lederer Goldberg
Support type: Regular Research Grants