Xenogenous Collagen Matrix and/or Enamel Matrix Derivative for Treatment of Localized Gingival Recessions: A Randomized Clinical Trial. Part II: Patient-Reported Outcomes

Author(s)

dos Santos, Manuela Rocha ^[1] ; Menck Sangiorgio, Joao Paulo ^[1] ; da Silva Neves, Felipe Lucas ^[2] ; Franca-Grohmann, Isabela Lima ^[1] ; Nociti, Jr., Francisco Humberto ^[1] ; Silverio Ruiz, Karina Gonzales ^[1] ; Santamaria, Mauro Pedrine ^[2] ; Sallum, Enilson Antonio ^[1]

Affiliation

^[1] Univ Estadual Campinas, Piracicaba Dent Sch, Div Periodont, Dept Prosthesis & Periodontol, Campinas, SP - Brazil

^[2] State Univ, Div Periodont, Dept Diag & Surg, Sao Paulo Campus, Sao Jose Dos Campos - Brazil

• Document type: Journal article
• Source: Journal of Periodontology; v. 88, n. 12, p. 1319-1328, DEC 2017.
• Web of Science Citations: 7

Abstract

Background: Gingival recession (GR) might be associated with patient discomfort due to cervical dentin hypersensitivity (CDH) and esthetic dissatisfaction. The aim is to evaluate the effect of root coverage procedure with a xenogenous collagen matrix (CM) and/or enamel matrix derivative (EMD) in combination with a coronally advanced flap (CAF) on CDH, esthetics, and oral health-related quality of life (OHRQoL) of patients with GR. Methods: Sixty-eight participants with single Miller Class I/II GRs were treated with CAF (n = 17), CAF + CM (n = 17), CAF + EMD (n = 17), and CAF + CM + EMD (n = 17). CDH was assessed by evaporative stimuli using a visual analog scale (VAS) and a Schiff scale. Esthetics outcome was assessed with VAS and the Questionnaire of Oral Esthetic Satisfaction. Oral Health Impact Profile-14 (OHIP-14) questionnaire was used to assess OHRQoL. All parameters were evaluated at baseline and after 6 months. Results: Intragroup analysis showed statistically significant reduction in CDH and esthetic dissatisfaction with no intergroup significant differences (P>0.05). The impact of oral health on QoL after 6 months was significant for CAF + CM, CAF + EMD, and CAF + CM + EMD (P<0.05). Total OHIP-14 score and psychologic discomfort, psychologic disability, social disability, and handicap dimensions showed negative correlation with esthetics. OHIP-14 physical pain dimension had positive correlation with CDH (P<0,05). OHIP-14 showed no correlation with percentage of root coverage, keratinized tissue width, or keratinized tissue thickness (P>0.05). Conclusion: Root coverage procedures improve patient OHRQoL by impacting on a wide range of dimensions, perceived after reduction of CDH and esthetic dissatisfaction of patients with GRs treated with CAF + CM, CAF + EMD, and CAF + CM + EMD. (AU)

• FAPESP's process: 13/19473-6 - Xenogenous collagen matrix graft with or without enamel matrix proteins derivative in the treatment of Miller class I and II gingival recessions
• Grantee: Enilson Antonio Sallum
• Support Opportunities: Regular Research Grants