| Full text | |
| Author(s): |
Total Authors: 4
|
| Affiliation: | [1] Univ Sao Paulo, Bioinformat Grad Program, Sao Carlos, SP - Brazil
[2] Univ Fed Sao Carlos, Dept Comp Sci, Sao Carlos, SP - Brazil
[3] Univ Sao Paulo, Sao Carlos Inst Phys, POB 369, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | INTEGRATIVE BIOLOGY; v. 9, n. 12, p. 947-955, DEC 2017. |
| Web of Science Citations: | 1 |
| Abstract | |
Complex networks have been widely used to model biological systems. The concept of accessibility has been proposed recently as a means to organize the nodes of complex networks as belonging to its border or center. Such an approach paves the way to investigating how the functional and structural properties of nodes vary with their respective position in the networks. In this work, we approach such a problem in a biological context applying border detection to Protein-Protein Interaction networks from four organisms of the Mycoplasma genus. We found evidence that the borderness of proteins bears a relation with their spatial organization and molecular function specificity. (AU) | |
| FAPESP's process: | 15/08003-4 - Complex network approach to e-Science and dynamic datasets |
| Grantee: | Filipi Nascimento Silva |
| Support type: | Scholarships in Brazil - Post-Doctorate |
| FAPESP's process: | 15/18942-8 - Associating Complex Networks with Effective Feature Spaces |
| Grantee: | Cesar Henrique Comin |
| Support type: | Scholarships in Brazil - Post-Doctorate |
| FAPESP's process: | 11/50761-2 - Models and methods of e-Science for life and agricultural sciences |
| Grantee: | Roberto Marcondes Cesar Junior |
| Support type: | Research Projects - Thematic Grants |