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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Biological network border detection

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Burke, Paulo E. P. [1] ; Comin, Cesar H. [2] ; Silva, Filipi N. [3] ; Costa, Luciano da F. [3]
Total Authors: 4
[1] Univ Sao Paulo, Bioinformat Grad Program, Sao Carlos, SP - Brazil
[2] Univ Fed Sao Carlos, Dept Comp Sci, Sao Carlos, SP - Brazil
[3] Univ Sao Paulo, Sao Carlos Inst Phys, POB 369, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: INTEGRATIVE BIOLOGY; v. 9, n. 12, p. 947-955, DEC 2017.
Web of Science Citations: 1

Complex networks have been widely used to model biological systems. The concept of accessibility has been proposed recently as a means to organize the nodes of complex networks as belonging to its border or center. Such an approach paves the way to investigating how the functional and structural properties of nodes vary with their respective position in the networks. In this work, we approach such a problem in a biological context applying border detection to Protein-Protein Interaction networks from four organisms of the Mycoplasma genus. We found evidence that the borderness of proteins bears a relation with their spatial organization and molecular function specificity. (AU)

FAPESP's process: 11/50761-2 - Models and methods of e-Science for life and agricultural sciences
Grantee:Roberto Marcondes Cesar Junior
Support type: Research Projects - Thematic Grants
FAPESP's process: 15/18942-8 - Associating Complex Networks with Effective Feature Spaces
Grantee:Cesar Henrique Comin
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 15/08003-4 - Complex network approach to e-Science and dynamic datasets
Grantee:Filipi Nascimento Silva
Support type: Scholarships in Brazil - Post-Doctorate