Evaluating the effects of the adulterants in milk using direct-infusion high resolution mass spectrometry

Author(s)

Guerreiro, Tatiane Melina ^[1] ; de Oliveira, Diogo Noin ^[1] ; Odir Rodrigues Melo, Carlos Fernando ^[1] ; Lima, Estela de Oliveira ^[1] ; Ribeiro, Marta da Silva ^[1] ; Catharino, Rodrigo Ramos ^[1]

Affiliation

^[1] Univ Estadual Campinas, UNICAMP, Sch Pharmaceut Sci, Innovare Biomarkers Lab, Campinas, SP - Brazil

• Document type: Journal article
• Source: Food Research International; v. 108, p. 498-504, JUN 2018.
• Web of Science Citations: 1

Abstract

Milk is an extremely complex food, capable of providing essential nutrients as well as being an important source of energy, and high-quality proteins and fats. Due to advances in technology, and to meet the increasing demand, production costs have increased, turning milk into a target of adulterations. Routine methods usually applied to certify the quality of the milk are restricted to microbiological tests, and assays that attest the nutritional composition within the expected values. However, potentially harmful byproducts generated by adulterating substances in general are not detected through these methodologies. In this contribution, we simulated the adulteration of freshly produced milk samples with four adulterants whose use already had reported for extended shelf life: formaldehyde, hydrogen peroxide, sodium hydroxide, and sodium hypochlorite. These samples were submitted to direct-infusion high-resolution mass spectrometry analysis and multivariate statistical analysis. This approach allows the characterization of a series of molecules modified by the adulterants, what demonstrates how these species affect the nutritious characteristics of this product. (AU)

• FAPESP's process: 15/06809-1 - Determination of chemical markers in various bovine products using mass spectrometry
• Grantee: Rodrigo Ramos Catharino
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/17066-2 - Metabolomics and lipidomics the Zika virus, from mosquitoes to the patient
• Grantee: Carlos Fernando Odir Rodrigues Melo
• Support Opportunities: Scholarships in Brazil - Doctorate