| Full text | |
| Author(s): |
Goldberg, Daphne W.
[1]
;
Fernandes, Miriam R.
[2]
;
Sellera, Fabio P.
[3]
;
Costa, Daniela G. C.
[4]
;
Loureiro Bracarense, Ana Paula
[5]
;
Lincopan, Nilton
[6, 2]
Total Authors: 6
|
| Affiliation: | [1] Univ Estadual Londrina, Postgrad Program Anim Sci, Dept Vet Prevent Med, Londrina - Brazil
[2] Univ Sao Paulo, Sch Pharm, Dept Clin Anal, Sao Paulo - Brazil
[3] Univ Sao Paulo, Dept Internal Med, Sch Vet Med & Anim Sci, Sao Paulo - Brazil
[4] Pro Tamar Fdn, Ubatuba, SP - Brazil
[5] Univ Estadual Londrina, Lab Anim Pathol, Vet Med Dept, Londrina - Brazil
[6] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Sao Paulo - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | ZOONOSES AND PUBLIC HEALTH; v. 66, n. 5, p. 540-545, AUG 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
CTX-M-type extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae have become identified in marine ecosystem constituting a serious ecological issue. In this respect, although contamination of coastal waters and seafood, and even colonization of seabirds and fishes have been increasingly reported, molecular data are lacking to elucidate the clinical impact of ESBL producers in infected marine animals. In this study, using a genomic approach, we have analysed the genetic background of CTX-M-15-producing Enterobacter hormaechei (belonging to the international human clone ST114) and Citrobacter freundii (ST265) co-infecting a free-living green turtle (Chelonia mydas) suffering from septic arthritis, which progressed to generalized coelomitis and death. Wide resistome of these pathogens contributed to treatment failure and death of the animal. (AU) | |
| FAPESP's process: | 15/13527-2 - Ancestral relationship, pan-resistoma plasmid of Escherichia coli producing b-lactamases of extended spectrum (CTX-M) and of plasmid curing methods |
| Grantee: | Miriam Rodriguez Fernandes |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 16/08593-9 - Pan-Resistome of beta-lactamase (KPC-2, CTX-M-8, CTX-M-15)-producing Klebsiella pneumoniae and Escherichia coli isolates endemic in Brazil |
| Grantee: | Nilton Erbet Lincopan Huenuman |
| Support Opportunities: | Regular Research Grants |