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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Relating mechanical properties of vertebral trabecular bones to osteoporosis

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Cesar, R. [1] ; Bravo-Castillero, J. [2, 3] ; Ramos, R. R. [4] ; Pereira, C. A. M. [5] ; Zanin, H. [6] ; Rollo, J. M. D. A. [7]
Total Authors: 6
[1] Univ Sao Paulo, Dept Mech Engn, Sao Carlos Sch Engn, Sao Carlos, SP - Brazil
[2] Univ Nacl Autonoma Mexico, IIMAS, Mexico City, DF - Mexico
[3] Parque Cient Tecnol Yucatan, Unidad Acad Yucatan, IIMAS UNAM Merida, Merida, Yucatan - Mexico
[4] Univ La Habana, Fac Matemat & Comp, Havana - Cuba
[5] Univ Sao Paulo, Orthoped & Traumatol Inst, Clin Hosp, Sao Paulo, SP - Brazil
[6] Univ Estadual Campinas, Carbon Sci Tech Labs, Sch Elect & Comp Engn, Campinas, SP - Brazil
[7] Univ Sao Paulo, Dept Mat Engn, Sao Carlos Sch Engn, Sao Carlos, SP - Brazil
Total Affiliations: 7
Document type: Journal article
Web of Science Citations: 0

Osteoporosis is an osteometabolic disease, which promotes structural degradation of bone tissue and reduction of mineral density. We reported here a mechanical resistance assay from normal, osteopenic and osteoporotic trabecular vertebral bones of human cadavers. We performed a compressed test on ninety samples, evaluating Young's modulus and X-ray microtomography to measure bone volume fraction and trabecular thickness. This experimental data are employed for computing the orthotropic macroscopic behavior of vertebral trabecular bones using known analytical formulae that were obtained by Galka et al. (Arch Mech 51: 335-355, 1999) via an asymptotic homogenization model. A geometrical model with a periodic orthogonal plate-like structure is applied. The properties of the bone-trabecular mass are considered linear, homogeneous and orthotropic. Average values for all technical or engineering elastic properties are computed for three important regions of the trabecular bones corresponding to thirty individuals classified as normal, osteopenic or osteoporotic by calcaneus ultrassometry. This study could be useful for a better understanding of the elastic behavior of trabecular bones in human vertebral bodies, allowing an estimation of bone answer under stress in different directions and the risk of fracture associated with osteoporosis. (AU)

FAPESP's process: 14/02163-7 - Development of supercapacitors devices from graphene, carbon nanotubes and diamonds
Grantee:Hudson Giovani Zanin
Support type: Research Grants - Young Investigators Grants