| Full text | |
| Author(s): |
Total Authors: 2
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| Affiliation: | [1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Analises Clin Toxicol & Bromatol, Ribeirao Preto - Brazil
Total Affiliations: 1
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| Document type: | Journal article |
| Source: | WATER AIR AND SOIL POLLUTION; v. 231, n. 7 JUN 17 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
The plasmid-borne mobilized colistin resistance genes (mcr-like) are related to resistance to polymyxins, which were reintroduced for the treatment of infections caused by multidrug-resistant pathogens. To analyze the presence of clinically relevant antimicrobial resistance genes (ARGs), includingmcr-like genes and plasmids in a beach, sand samples from a public beach were collected. Fifty-seven amplicons from 22 ARGs [mcr-4,bla(VIM),bla(CTX-M-Gp9),bla(PER),bla(CMY),qnrB,qnrS,oqxA,oqxB,sul1,sul2,sul3,floR,cmlA,tetA,tetB,tetC,aadA,ant(2 '')-Ia,aph(3 ')-Ib,aac(6 ')-Ib, andmefAE] and 18 amplicons from seven plasmid families (IncF(repB), IncFIA, IncHI1, IncFIB, IncY, IncN, and ColE-like) were detected. To the best of our knowledge, this is the first report of themcr-4gene in Brazil and the first report in the world ofmcr-4gene in a recreation area. This study calls attention to the presence ofmcr-4gene and contribute to the surveillance studies about themcr-like genes. (AU) | |
| FAPESP's process: | 18/01890-3 - Study of resistance, virulence and epidemiological profile of Escherichia coli isolated from environment |
| Grantee: | João Pedro Rueda Furlan |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 18/19539-0 - Molecular characterization of Escherichia coli isolates from the environment |
| Grantee: | Eliana Guedes Stehling |
| Support Opportunities: | Regular Research Grants |