| Full text | |
| Author(s): |
Porto Goncalves, Thiago Correa
[1]
;
Trape, Atila Alexandre
[2]
;
Lima Rodrigues, Jhennyfer Aline
[2]
;
Tavares, Simone Sakagute
[3, 1]
;
Bueno Junior, Carlos Roberto
[3, 1, 2, 4]
Total Authors: 5
|
| Affiliation: | [1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Ribeirao Preto - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Coll Nursing, Ribeirao Preto - Brazil
[3] Univ Sao Paulo, Sch Phys Educ & Sport Ribeirao Preto, Ribeirao Preto - Brazil
[4] Bueno Junior, Carlos Roberto, Univ Sao Paulo, Sch Phys Educ \& Sport Ribeirao Preto, Ribeirao Preto, Brazil.Porto Goncalves, Thiago Correa, Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Ribeirao Preto - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | JOURNAL OF AGING AND PHYSICAL ACTIVITY; v. 28, n. 2, p. 242-249, APR 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
The beta(2) adrenergic receptor (beta(2)-AR) plays an important role in vascular smooth muscle. However, the interaction between Arg16Gly and Gln27Glu beta(2)-AR polymorphisms, and exercise training has not yet been established. This study evaluated the influence of these beta(2)-AR polymorphisms on body composition, aerobic capacity, blood pressure, lipid profile, nitric oxide, and redox status at baseline and in response to an exercise program in women aged 50-79 years. Genotype and haplotypes were analyzed in association with the previously mentioned variables before and after the multicomponent training (12 weeks, 2 sessions/week, 90 min/session, and exercise intensity between 13 and 15 on the Borg scale). Individuals who carry beta(2)-AR Arg16Arg/Gln27Gln genotypes presented more improvements in blood pressure, body composition, aerobic capacity, and redox status in response to a multicomponent training program compared with individuals who do not carry this haplotype. In some years, the genetic profile may be used to predict which exercise program can induce more health benefits for each person. (AU) | |
| FAPESP's process: | 13/21159-8 - Influence of genetics polymorphisms in effects of two types of high intensity aerobic interval training in patients with metabolic syndrome |
| Grantee: | Carlos Roberto Bueno Júnior |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 17/21361-2 - Global screening of genetic and epigenetic factors associated with magnitude of response to different physical training protocols in women 50-70 years |
| Grantee: | Carlos Roberto Bueno Júnior |
| Support Opportunities: | Regular Research Grants |