| Full text | |
| Author(s): |
Ataide, Vanessa N.
[1]
;
Ameku, Wilson A.
[1]
;
Bacil, Raphael R.
[1]
;
Angnes, Lucio
[1]
;
de Araujo, William R.
[2]
;
Paixao, Thiago R. L. C.
[1]
Total Authors: 6
|
| Affiliation: | [1] Sao Paulo Univ USP, Inst Chem, Dept Fundamental Chem, BR-05508900 Sao Paulo, SP - Brazil
[2] Univ Estadual Campinas, UNICAMP, Inst Chem, Dept Analyt Chem, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | RSC ADVANCES; v. 11, n. 3, p. 1644-1653, JAN 13 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Electrochemical Paper-based Analytical Devices (ePADs) are an alternative to traditional portable analytical techniques due to features such as low-cost, easy surface modification with different materials, and high sensitivity. A fast and simple method to fabricate enhanced ePADs using pencil-drawing which involves the CO2 laser treatment of the carbon surface deposited on paper is described. The electrochemical performances of the devices were evaluated using cyclic voltammetry (CV) with different redox probes and electrochemical impedance spectroscopy (EIS). The electrochemical results show that a treated surface presents a lower resistance to charge transfer and changes the approach of the probe and the overlap of its orbitals with the electrode. To investigate the effects of the laser treatment process, chemical and structural characteristics were evaluated using scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. These results indicated that laser treatment promoted the restoration of carbon-carbon double bonds and removed a thin layer of nanodebris present in commercial pencils, resulting in an improvement of the electrochemical kinetics. As a proof-of-concept, the Pencil-Drawing Electrode (PDE) was used for the detection and quantification of furosemide (FUR) in a sample of synthetic urine, exhibiting a limit of detection (LOD) of 2.4 x 10(-7) mol L-1. The percentages of recovery of the FUR added to the samples A and B were 95% and 110%, respectively. The analysis using CO2 laser-treated PDE resulted in a fast, simple, and reliable method for this doping agent. (AU) | |
| FAPESP's process: | 18/14462-0 - Fabrication of electrochemical paper-based device aiming clinical and environmental applications |
| Grantee: | Vanessa Neiva de Ataide |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 16/21070-5 - Vibrational spectroscopy with spatial resolution |
| Grantee: | Mauro Carlos Costa Ribeiro |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 18/08782-1 - Miniaturized and integrated chemical sensors: new fabrication platforms for biological, clinical and environmental applications |
| Grantee: | Mauro Bertotti |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 16/16477-9 - Fabrication of portable paper-based analytical devices with electrochemical and colorimetric detection system aiming at forensic, clinical, and environmental applications |
| Grantee: | William Reis de Araujo |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 17/10522-5 - Development of alternative methods for fabrication of electrochemical paper-based sensors |
| Grantee: | Thiago Regis Longo Cesar da Paixão |
| Support Opportunities: | Regular Research Grants |