| Full text | |
| Author(s): Show less - |
Castello-Simoes, Viviane
[1]
;
Kabbach, Erika Zavaglia
[1]
;
Schafauser, Nathany Souza
[1]
;
Camargo, Patricia Faria
[1]
;
Simoes, Rodrigo Polaquini
[1, 2]
;
Heubel, Alessandro Domingues
[1]
;
Alqahtani, Jaber Saud
[3, 4]
;
da Cunha Martino Pereira, Mariana Brasil
[1]
;
Sgarbosa, Nicole Marques
[1]
;
Borghi-Silva, Audrey
[1]
;
Mendes, Renata Goncalves
[1]
Total Authors: 11
|
| Affiliation: | [1] Fed Univ Sao Carlos UFSCar, Dept Physiotherapy, Cardiopulm Physiotherapy Lab, Rodovia Washington Luis, KM 235, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Fed Alfenas, UNIFAL, Postgrad Program Rehabil Sci, Rua Gabriel Monteiro da Silva 700, BR-37130001 Alfenas, MG - Brazil
[3] UCL, UCL Resp, Rowland Hill St, London NW3 2PF - England
[4] Prince Sultan Mil Coll Hlth Sci, Dept Resp Care, Dammam 34313 - Saudi Arabia
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | RESPIRATORY MEDICINE; v. 185, AUG-SEP 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Purpose: Impairment of cardiac autonomic integrity is common in chronic obstructive pulmonary disease (COPD) patients. The influence of the interaction between clinical and severity status on brain-heart autonomic axis (BHAA) is not well known. We aimed to investigate the BHAA function across different clinical status and severity of COPD. Methods: Cross-sectional study involving 77 COPD patients allocated into four groups according to clinical status {[}acute exacerbation (GAE) or stable (GST)] and severity {[}less (-) or more (+)]: 1) GAE-, n = 13; 2) GAE+, n = 20; 3) GST-, n = 23; and 4) GST+, n = 21. Heart rate variability (HRV) at rest and heart rate recovery (HRR) after 6-min walk test were markers of BHAA. Mean R-R, STDRR, RMSSD, RRtri, HF, LF, SD1, SD2, ApEn and SampEn were the HRV indexes and, HRR was obtained as: HR at 1st min of recovery minus peak HR. Results: A main effect of clinical status (p < 0.001) was found to vagal modulation in GAE-vs. GST- (RMSSD: 25.0 +/- 14.8 vs. 12.6 +/- 5.5 ms; SD1: 18.0 +/- 10.6 vs. 8.9 +/- 3.9 ms) and to GAE + vs. GST+ (RMSSD: 26.4 +/- 15.2 vs. 15.4 +/- 6.3 ms; SD1: 18.3 +/- 11.2 vs. 10.9 +/- 4.5 ms). An effect of clinical status (p = 0.032) and severity (p = 0.030) were found to HF (vagal) in GAE + compared to GAE- and GST+ (264.7 +/- 239.0 vs. 134.7 +/- 169.7 and 135.8 +/- 139.7 ms2). Lower HRR was found in GAE-compared to GST- (8.0 +/- 2.4 vs. 19.6 +/- 2.4 bpm), p = 0.002. Conclusion: In COPD patients, clinical status (AECOPD or stable) was more dominant than the severity on BHAA function. A more pronounced parasympathetic modulation was found in AECOPD patients with a lower HRR to exercise. (AU) | |
| FAPESP's process: | 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach |
| Grantee: | Audrey Borghi Silva |
| Support Opportunities: | Research Projects - Thematic Grants |