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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Comparative Highly Efficient Production of beta-glucan by Lasiodiplodia theobromae CCT 3966 and Its Multiscale Characterization

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Author(s):
Ascencio, Jesus J. [1] ; Philippini, Rafael R. [1] ; Gomes, Fabricio M. [2] ; Pereira, Felix M. [2] ; da Silva, Silvio S. [1] ; Kumar, Vinod [3] ; Chandel, Anuj K. [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Engn Sch Lorena, Dept Biotechnol, Estr Municipal Campinho S-N, BR-12602810 Lorena, SP - Brazil
[2] Univ Sao Paulo, Engn Sch Lorena, Dept Chem Engn, Estr Municipal Campinho S-N, BR-12602810 Lorena, SP - Brazil
[3] Cranfield Univ, Ctr Climate & Environm Protect, Sch Water Energy & Environm, Cranfield MK43 0AL, Beds - England
Total Affiliations: 3
Document type: Journal article
Source: FERMENTATION-BASEL; v. 7, n. 3 SEP 2021.
Web of Science Citations: 1
Abstract

Lasiodiplodan, a (1 -> 6)-beta-d-glucan, is an exopolysaccharide with high commercial value and many applications in food, pharmaceuticals, and cosmetics. Current industrial production of beta-glucans from crops is mostly by chemical routes generating hazardous and toxic waste. Therefore, alternative sustainable and eco-friendly pathways are highly desirable. Here, we have studied the lasiodiplodan production from sugarcane bagasse (SCB), a major lignocellulosic agricultural residue, by Lasiodiplodia theobromae CCT 3966. Lasiodiplodan accumulated on SCB hydrolysate (carbon source) supplemented with soybean bran or rice bran (nitrogen source) was 16.2 {[}6.8 x 10(3) Da] and 22.0 {[}7.6 x 10(3) Da] g/L, respectively. Lasiodiplodan showed high purity, low solubility, pseudoplastic behavior and was composed of glucose units. Moreover, the exopolysaccharides were substantially amorphous with moderate thermal stability and similar degradation temperatures. To our knowledge, this is the first report on the highest production of SCB-based lasiodiplodan to date. L. theobromae, as a microbial cell factory, demonstrated the commercial potential for the sustainable production of lasiodiplodan from renewable biomass feedstock. (AU)

FAPESP's process: 16/10636-8 - From the cell factory to the Biodiesel-Bioethanol integrated biorefinery: a systems approach applied to complex problems in micro and macroscales
Grantee:Roberto de Campos Giordano
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Thematic Grants
FAPESP's process: 16/14852-7 - A sustainable solution against neglected tropical diseases using biosurfactants produced by yeasts in sugarcane bagasse hemicellulosic hydrolyzate
Grantee:Paulo Ricardo Franco Marcelino
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 14/18714-2 - Enzymatic oxidation of sugarcane bagasse: discovery, characterization and new application of oxidative enzymes active in carbohydrates, applied to the enhancement of a fungal cell factory
Grantee:Fernando Segato
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Young Investigators Grants
FAPESP's process: 08/57926-4 - Research and development aiming at the integrated exploitation of sugarcane bagasse for the biotechnological production of lignocellulosic ethanol
Grantee:Silvio Silvério da Silva
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Thematic Grants