The effect of photodynamic therapy on postoperative pain in teeth with primary endodontic infection

Author(s):Show less -

Alves-Silva, Esdras Gabriel ^[1] ; Arruda-Vasconcelos, Rodrigo ^[1] ; Louzada, Lidiane Mendes ^[1] ; de-Jesus-Soares, Adriana ^[1] ; Ferraz, Caio Cezar Randi ^[1] ; Almeida, Jose Flavio Affonso ^[1] ; Marciano, Marina Angelica ^[1] ; Steiner-Oliveira, Carolina ^[2] ; Bello-Silva, Marina Stella ^[3] ; Shemesh, Hagay ^{[4, 5]} ; Gomes, Brenda Paula Figueiredo de Almeida ^[1]

Affiliation

^[1] Univ Estadual Campinas, Piracicaba Dent Sch, Div Endodont, Dept Restorat Dent, UNICAMP, POB 52, BR-13414903 Piracicaba, SP - Brazil

^[2] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Hlth Sci & Pediat Dent, UNICAMP, Piracicaba, SP - Brazil

^[3] Univ Sao Paulo, Dept Restorat Dent, Sch Dent, Special Lab Lasers Dent LELO, Sao Paulo, SP - Brazil

^[4] Vrije Univ Amsterdam, Amsterdam - Netherlands

^[5] Univ Amsterdam, Acad Ctr Dent Amsterdam ACTA, Dept Endodontol, Amsterdam - Netherlands

• Document type: Journal article
• Source: Photodiagnosis and Photodynamic Therapy; v. 37, MAR 2022.
• Web of Science Citations: 0

Abstract

Introduction: : The objective of this study was to investigate the action of photodynamic therapy on pain control after endodontic treatment in asymptomatic teeth with a primary infection, within a single visit. Methods: : Sixty (60) single-rooted teeth with pulp necrosis and periapical lesions were selected and randomly divided into two (2) groups (n = 30), according to the protocol; a control group (CG) and a group using photodynamic therapy (aPDT). The canals were instrumented with Reciproc files \# 25 up to 40 along the entire length of the canal, using 2% chlorhexidine gel as the auxiliary chemical substance, followed by irrigation with sterile saline. aPDT consited of 0.005% methylene blue as photosensitizer, using AsGaAl diode laser, 660 nm wavelength, 100 mW of power and 9 J of energy, using optical fibers with 365 pm in diameter. The canals were filled with Endomethasone N cement. Results: : Pain intensity was assessed at 8, 12, 24, 48, 72 h and 1 week after endodontic treatment using a visual analogue scale. The level of pain was classified as none (0), mild (1-3), moderate (4-7) or severe (8-10). The data were at a significance level of 5%. There was a statistically significant difference (p<0.05) in the periods of 8, 12, 24, 48 and 72 h between the control group and the aPDT group. After 1 week, there was no statistically significant difference. Conclusions: : It is concluded that photodynamic therapy had a significant effect on decreasing post-endodontic treatment pain in teeth with necrotic pulp and asymptomatic periapical lesions. (AU)

• FAPESP's process: 19/19300-0 - Investigation of the clinical, microbiological and immunological aspects of teeth with diagnosis of primary periodontal lesions with secondary endodontic involvement
• Grantee: Lidiane Mendes Louzada
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 17/25242-8 - Clinical, microbiological and immunological monitoring of patients undertaken to endodontic therapy with diagnosis of irreversible Pulpitis
• Grantee: Rodrigo Arruda Vasconcelos
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 19/10755-5 - Clinical investigation of epigenetic modulations in dental pulp tissues with diagnosis of irreversible pulpitis
• Grantee: Rodrigo Arruda Vasconcelos
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• FAPESP's process: 15/23479-5 - Microbiomes and immunobiological aspects in endodontic infections
• Grantee: Brenda Paula Figueiredo de Almeida Gomes
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 19/09115-1 - Effect of chemomechanical preparation associated with photodynamic therapy in the reduction of microbial, LPS, LTA, substance p and pro-inflammatory cytokines in primary endodontic infection
• Grantee: Esdras Gabriel Alves e Silva
• Support Opportunities: Scholarships in Brazil - Master