Effect of amphiphilic ionic liquids on the colorimetric properties of polyketides colorants

Author(s)

Verissismo, Nathalia V. ; Nakamura, Cecilia Naomi ; de Oliveira, Fernanda ; Kuhn, Bruna L. ; Frizzo, Clarissa P. ; Pereira, Jorge F. B. ; Santos-Ebinuma, Valeria C.

• Document type: Journal article
• Source: JOURNAL OF MOLECULAR LIQUIDS; v. 363, p. 11-pg., 2022-07-30.

Abstract

Consumers are currently pressuring the food industries to replace synthetic colorants with their natural counterparts. However, natural colorants still represent less than a third of food coloring additives, as they are more difficult to produce and present application issues due to their lower stability. To find sur-factants compatible with natural colorants, this study evaluated the effect of amphiphilic ionic liquids (ILs) aqueous solutions on the colorimetric properties of polyketides colorants (yellow-orange and red color) produced by Talaromyces amestolkiae. Only the IL n-alkyl-3-methylimidazolium bromide ([Cnmim]Br with n = 10) at 2.5 mM preserved the colorimetric and fluorescence characteristics of the fun-gal colorants, while the other surfactants [e.g., [Cnmim]Br with n = 12, 14, and 16, tributyl-tetradecylphosphonium chloride ([P4,4,4,14]Cl), and cetyltrimethylammonium bromide (CTAB)] altered them. Fluorescence was more sensitive to the effect of ILs than their color and absorbance. Furthermore, the red colorant was more affected by the ILs than the yellow-orange chromophores. Hence, this work shows that formulations with [C10mim]Br (up to 2.5 mM) can preserve the properties of T. amestolkiae polyketides colorants, while the other ILs can be used as additives to modulate their color and fluorescence for biosensing applications.(c) 2022 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 14/01580-3 - Biotechnological process for the development of new natural colorants from microorganisms for industrial application
• Grantee: Valéria de Carvalho Santos Ebinuma
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 14/16424-7 - Optimization and scale-up of liquid-liquid extraction process with ionic liquids (ILs) as a sustainable tool for the separation of the anti-leukemia biopharmaceutical L-asparaginase (ASPase)
• Grantee: Jorge Pereira
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 21/09175-4 - BIOREFINERY AS A PLATFORM FOR THE PRODUCTION OF FUNGAL COLORANTS
• Grantee: Fernanda de Oliveira
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/15493-9 - Development of ionic liquids-based electroconductive hydrogels
• Grantee: Valéria de Carvalho Santos Ebinuma
• Support Opportunities: Regular Research Grants
• FAPESP's process: 21/06686-8 - Biotechnological process for the development of natural colorants from microbial sources for industrial application: phase II
• Grantee: Valéria de Carvalho Santos Ebinuma
• Support Opportunities: Program for Research on Bioenergy (BIOEN) - Young Investigators Grants - Phase 2