The Effects of Different Exercise Training Types on Body Composition and Physical Performance in Older Adults with Sarcopenic Obesity: A Systematic Review and Meta-Analysis

Author(s)

Goncalves, L. da Silva ; da Silva, Leonardo Santos Lopes ; Benjamim, C. J. Rodrigues ; Tasinafo Jr, M. F. ; Bohn, L. ; Abud, G. Ferreira ; Ortiz, G. U. ; de Freitas, E. C.

• Document type: Journal article
• Source: Journal of Nutrition Health & Aging; v. 27, n. 11, p. 15-pg., 2023-11-13.

Abstract

OBJECTIVES: To carry out a systematic review and meta-analysis to verify the effects of different exercise training types on body composition and physical performance in older adults with sarcopenic obesity (SO). DESIGN: Systematic review and meta-analysis. SETTING AND PARTICIPANTS: Older adults (>= 60 years). METHODS: Database searches were performed in MEDLINE (via PubMed), EMBASE, Cochrane Library, Web of Science, SCOPUS, and LILACS on January 10th, 2023. We included: randomized and/or controlled clinical trials; physical exercise as an intervention; analysis of body composition and/or muscle function; and sarcopenic obesity diagnosis. We used the Risk of Bias 2 tool and PEDro scale. The GRADE certainty of evidence was also performed. RESULTS: Fourteen studies were included in the systematic review and nine studies in the meta-analysis. A decrease in body fat (%) favoring the exercise group was identified (SMD:-0.34 [95% CI:-0.53 to-0.16]; p=0.0003) (GRADE: circle plus circle plus circle plus circle Moderate). Only resistance training showed fat reduction (SMD:-0.27 [95% CI:-0.48 to-0.06]; p=0.01). Increases in upper (SMD: 0.41 [95% CI: 0.04 to 0.78]; p=0.03) (GRADE: circle plus circle plus circle circle Low) and lower (SMD: 0.80 [95% CI: 0.22 to 1.39]; p=0.007) (GRADE: circle plus circle plus circle plus circle plus High) limb strength was identified with exercise. Chair stand test showed increases with exercise (SMD: 0.73 [95% CI: 0.40 to 1.07]; p<0.0001) (GRADE: circle plus circle plus circle plus circle plus High), especially for resistance training (SMD: 0.62 [95% CI: 0.21 to 1.02]; p=0.003) and combined training (SMD: 0.99 [95% CI: 0.40 to 1.57]; p=0.0005). The PEDro scale for the studies in our review ranged from 3 to 8 (mean = 5.8 (1.6)), meaning fair methodological quality, and most studies were overall judged with at least low/some concerns in terms of risk of bias. CONCLUSION AND IMPLICATIONS: Overall, moderate to high certainty of evidence was found for body fat, lower limb strength, and chair stand test. On the other hand, low certainty of evidence was found for upper limb strength. Resistance, combined, and aerobic training evoked divergent results between the variables analyzed. Although promising, our results should be considered sparingly, but may guide additional exercise recommendations to improve specific health parameters in older adults with SO. (AU)

• FAPESP's process: 22/06638-6 - Metabolic and molecular responses under the effect of taurine supplementation with and without multicomponent training in elderly women with sarcopenic obesity using the metabolomics approach.
• Grantee: Gabriela Ferreira Abud
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 22/00221-6 - Taurine supplementation associated or not with physical exercise: effect on the browning of white adipose tissue in elderly women with Sarcopenic Obesity
• Grantee: Gabriela Ueta Ortiz
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 22/07280-8 - SARCOPENIC OBESITY AND ASSOCIATIONS WITH MUSCLE STRENGTH AND PHYSICAL PERFORMANCE IN PHYSICALLY ACTIVE OLDER ADULTS
• Grantee: Leonardo Santos Lopes da Silva
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 19/11820-5 - Nr1d1 function on the aging-associated Sarcopenia
• Grantee: Adelino Sanchez Ramos da Silva
• Support Opportunities: Research Projects - Thematic Grants