| Full text | |
| Author(s): |
Illison, Vanessa K.
[1]
;
Rondo, Patricia H. C.
[1]
;
de Oliveira, Andreia M.
[1]
;
D'Abronzo, Francisco H.
[2]
;
Campos, Katia F.
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, BR-01246904 Sao Paulo - Brazil
[2] Jundiai Med Sch, Dept Internal Med, Jundiai, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH; v. 81, n. 1, p. 12-20, JAN 2011. |
| Web of Science Citations: | 8 |
| Abstract | |
Type 2 diabetes mellitus (DM2) predisposes to an increased production of free radicals and a probable reduction in plasma antioxidants, including vitamin E. This cross-sectional study investigated the relationship between plasma alpha-tocopherol concentration and vitamin E intake in 58 Brazilians with DM2. Plasma alpha-tocopherol was determined by high-performance liquid chromatography. The intake of vitamin E-rich foods was assessed by a food frequency questionnaire. Total cholesterol and fractions were measured by colorimetric enzymatic methods. Data on demographic and socioeconomic factors, life habits, and anthropometry were obtained by a questionnaire and physical examination. The association between plasma alpha-tocopherol and vitamin E intake was assessed by multiple linear regression analysis. The following variables were included in the regression model: alpha-tocopherol, vitamin E intake, total cholesterol and fractions, body mass index, waist circumference, gender, age, education, occupation, income, smoking, alcohol intake, and blood pressure. There was no association between alpha-tocopherol and vitamin E intake, but there were significant associations between alpha-tocopherol and total cholesterol (p < 0.001) and waist circumference (p = 0.003). There were 36.2 % diabetics with low alpha-tocopherol concentrations (< 12 mu mol/L) and 32.7 % with a low alpha-tocopherol/total cholesterol ratio (< 2.2). Further large, epidemiological, longitudinal studies, including measurements of gamma-tocopherol in blood, should be conducted to confirm our results. (AU) | |