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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A new overtraining protocol for mice based on downhill running sessions

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Pereira, Bruno C. [1] ; Filho, Luis A. L. [1] ; Alves, Guilherme F. [1] ; Pauli, Jose R. [2] ; Ropelle, Eduardo R. [2] ; Souza, Claudio T. [3] ; Cintra, Dennys E. [2] ; Saad, Mario J. A. [4] ; Silva, Adelino S. R. [1]
Total Authors: 9
[1] Univ Sao Paulo, Sch Phys Educ & Sport Ribeirao Preto, BR-14049 Ribeirao Preto - Brazil
[2] Univ Estadual Campinas, Fac Sci Appl, Sport Sci Course, Limeira - Brazil
[3] Univ So Santa Catarina, Hlth Sci Unit, Postgrad Program Hlth Sci, Exercise Biochem & Physiol Lab, Criciuma, Santa Catarina - Brazil
[4] Univ Estadual Campinas, Fac Med Sci, Dept Internal Med, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Clinical and Experimental Pharmacology and Physiology; v. 39, n. 9, p. 793-798, SEP 2012.
Web of Science Citations: 22

The purpose of the present study was to verify whether a downhill running protocol was able to induce non-functional overreaching in > 75% of mice. Mice were divided into control (C), trained (TR) and overtrained (OTR) groups. Bodyweight and food intake were recorded weekly. The incremental load test (ILT) and the exhaustive test (ET) were used to measure performance before and after aerobic training and overtraining protocols. Although the bodyweight of the OTR group was lower than that of the C group at the end of Week 7, the food intake of the OTR group was higher than that of the C and TR groups at the end of Week 8. Evaluation of results from the ILT and ET revealed significant intra- and inter-group differences: whereas the parameters measured by both tests increased significantly in the TR group, they were significantly decreased in the OTR group. In conclusion, this new overtraining protocol based on downhill running sessions induced non-functional overreaching in 100% of mice. (AU)

FAPESP's process: 11/02652-0 - Effects of training and overtraining on serum concentrations and muscular content of proinflammatory cytokines in mice
Grantee:Bruno Cesar Pereira
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 11/09864-2 - Comparison of muscular glycogen concentration, of GLUT-4 protein content, and of content and activation of proteins related to insulin signaling pathway in muscle of trained and overtrained mice
Grantee:Luís Armando Leonardo Filho
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 10/08239-4 - Mice in overtraining: relationships between the production of pro-inflammatory cytokines and the impairment of the molecular pathways of insulin signaling
Grantee:Adelino Sanchez Ramos da Silva
Support type: Regular Research Grants