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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cytocompatibility studies of vertically-aligned multi-walled carbon nanotubes: Raw material and functionalized by oxygen plasma

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Author(s):
Lobo, A. O. [1, 2, 3] ; Corat, M. A. F. [4] ; Antunes, E. F. [1, 2] ; Ramos, S. C. [1] ; Pacheco-Soares, C. [5] ; Corat, E. J. [1, 2]
Total Authors: 6
Affiliation:
[1] ITA, Sao Jose Dos Campos, SP - Brazil
[2] INPE, Lab Associado Sensores & Mat, Sao Jose Dos Campos, SP - Brazil
[3] Univ Vale do Paraiba, Lab Nanotecnol Biomed, Sao Jose Dos Campos, SP - Brazil
[4] Univ Estadual Campinas, Ctr Multidisciplinar Invest Biol Area Ciencia Ani, CEMIB, Campinas, SP - Brazil
[5] UNIVAP, Lab Dinam Compartimentos Celulares, Sao Jose Dos Campos, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Materials Science & Engineering C-Materials for Biological Applications; v. 32, n. 4, p. 648-652, MAY 1 2012.
Web of Science Citations: 17
Abstract

It was presented a strong difference on cell adhesion and proliferation of functionalized vertically-aligned multi-walled carbon nanotube (VACNT) scaffolds compared to raw-VACNT. Biocompatibility in vitro tests were performed on raw-VACNT after superficial modification by oxygen plasma, which changes its superhydrophobic character to superhydrophilic. Two cytocompatibility tests were applied: 1) total lactate dehydrogenase colorimetric assay for the study of proliferating cells; and 2) cellular adhesion by scanning electron microscopy. Results showed that superhydrophilic VACNT scaffolds stimulate cell growth with proliferation up to 70% higher than normal growth of cell culture. (c) 2010 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 07/00013-4 - New materials, studies and applications of CVD diamond, diamond-like-carbon (DLC) and nanostructured carbon obtained by chemical vapor deposition
Grantee:Evaldo Jose Corat
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 08/11642-5 - Development of structures based on carbon nanotubes, bioresorbable polymers and carbon fibers for studies with regenerative cells and hematopoietic stem cells
Grantee:Anderson de Oliveira Lobo
Support Opportunities: Scholarships in Brazil - Doctorate