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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Effects of Green Tea Consumption on Cardiometabolic Alterations Induced by Experimental Diabetes

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Author(s):
Fiorino, Patricia [1] ; Evangelista, Fabiana Sant'Anna [2] ; Santos, Fernando [1] ; Motter Magri, Fatima Maria [1] ; Delorenzi, Jan Carlo Morais O. B. [1] ; Ginoza, Milton [1] ; Farah, Vera [1]
Total Authors: 7
Affiliation:
[1] Univ Prebiteriana Mackenzie, Renal Cardiovasc & Metab Physiopharmacol Lab, Hlth & Biol Sci Ctr, BR-01302907 Sao Paulo - Brazil
[2] Univ Prebiteriana Mackenzie, Sch Arts Sci & Humanities, BR-01302907 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Experimental Diabetes Research; 2012.
Web of Science Citations: 7
Abstract

We evaluated cardiac autonomic modulation by heart rate (HRV), and arterial pressure variability (APV), and metabolic response in streptozotocin diabetic rats treated with green tea. Male Wistar rats were separated in groups: control, drinking tap water (C), green tea-treated (GT) group, diabetic, drinking tap water (D), and diabetic, treated with green tea (DGT). Kidney mass was greater in D and DGT than in C and GT, but reduced in DGT compared to D. Green tea prevented the increase in creatinine clearance and reduced hyperglycemia in DGT compared to D. Arterial pressure was increased in GT and decreased in D compared to C. HRV was reduced in D compared with all groups. APV was decreased in D compared to C and recovery in DGT. Sympathetic modulation of APV was decreased in D compared with all groups. Green tea reduced hyperglycemia, prevented renal injury and autonomic dysfunction, suggesting reduced cardiovascular risk and target organ damage in diabetes. (AU)

FAPESP's process: 09/52556-7 - Influence of salt levels in renal profile and cardiovascular function in an experimental model of insulin resistance: role of renin-angiotensin system
Grantee:Vera de Moura Azevedo Farah
Support type: Regular Research Grants
FAPESP's process: 11/02126-6 - Metabolic repercussion of physical training-induced AMPK activation in mice submitted to hypercaloric diet
Grantee:Fabiana de Sant'Anna Evangelista
Support type: Regular Research Grants