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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Calcification in vitro of Biomineralizated Nanohydroxyapatite/Superydrophilic Vertically Aligned Multiwalled Carbon Nanotube Scaffolds

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Author(s):
Neves, Marcele Florencio [1] ; Silva, Gislene Rodrigues [1] ; Brazil, Tayra Rodrigues [1] ; Marciano, Fernanda Roberta [1] ; Pacheco-Soares, Cristina [2] ; Lobo, Anderson Oliveira [1]
Total Authors: 6
Affiliation:
[1] Univ Vale Paraiba UniVap, Lab Nanotecnol Biomed, BR-12224000 Sao Jose Dos Campos, SP - Brazil
[2] Univ Vale Paraiba UniVap, Lab Dinam Compartimentos Celulares, BR-12224000 Sao Jose Dos Campos, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS; v. 16, n. 3, p. 614-618, MAY-JUN 2013.
Web of Science Citations: 3
Abstract

Nanocomposites based on superhydrophilic vertically aligned multi-walled carbon nanotubes (VAMWCNT-O-2) and nanohydroxyapatite (nHAp) are of great interest in bone regenerative medicine. The biomineralization using simulated body fluid (SBF) has been extensively studied to evaluate the bioactivity of biomaterials. Thus, the combination of nHAp and VAMWCNT-O-2 is attractive and promising. The aim of this study was to evaluate the in vitro calcification of nHAp/VAMWCNT-O-2 nanocomposites before and after the period of biomineralization in SBF. In vitro calcification of the extracellular matrix (ECM) of HOB cells in culture after 24 hours was investigated through the assay of alkaline phosphatase. These promising in vitro results validate biomineralized nHAp/VAMWCNT-O-2 as possible scaffolds for bone tissue regeneration. (AU)

FAPESP's process: 11/17877-7 - Development of new polymeric scaffolds by electrospinning technique with incorporation of vertically aligned carbon nanotubes and nanohidroxyapatite for bone tissue regeneration
Grantee:Anderson de Oliveira Lobo
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 12/02159-4 - In vitro analysis of the biomineralization and cell proliferation on nanohydroxyapatite/vertically aligned carbon nanotube scaffolds
Grantee:Tayra Rodrigues Brazil
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 11/20345-7 - Study of nanoparticle-incorporated diamond-like carbon films for biomedical applications
Grantee:Fernanda Roberta Marciano
Support type: Research Grants - Young Investigators Grants