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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

In Vitro Biomineralization of a Novel Hydroxyapatite/Superhydrophilic Multiwalled Carbon Nanotube Nanocomposite using Simulated Body Fluids

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Neves, Marcele Florencio [1] ; Brazil, Tayra Rodrigues [1] ; Silva Soares, Luis Eduardo [2] ; Corat, Evaldo Jose [3] ; Marciano, Fernanda Roberta [1] ; Lobo, Anderson Oliveira [1]
Total Authors: 6
[1] Univ Vale Paraiba UniVap, Inst Res & Dev IP&D, Lab Biomed Nanotechnol NANOBIO, BR-12244000 Sao Jose Dos Campos, SP - Brazil
[2] Univ Vale Paraiba UniVap, Inst Res & Dev IP&D, Lab Biomed Vibrat Spect LEVB, BR-12244000 Sao Jose Dos Campos, SP - Brazil
[3] Natl Inst Space Res INPE, Associated Lab Sensors & Mat LAS, BR-12227010 Sao Jose Dos Campos, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Web of Science Citations: 0

Nanobiomaterials based on superhydrophilic vertically-aligned multi-walled carbon nanotubes (VAMWCNT-O-2) are promising for their properties and bone tissue biocompatibility. VAMWCNT-O2 films with nanohydroxyapatite (nHAp) aim to improve mechanical properties and biocompatibility of this new nanocomposite due to its resemblance to bone matrix structure. This study aimed to produce in vitro biomineralized nHAp/VAMWCNT-O-2 nanocomposites using simulated body fluid (SBF) with two different pHs (6.10 and 7.40) during 7 days to obtain a new surface design with higher crystalinity and better morphology of nHAp/VAMWCANT-O-2 nanocomposites. The objective is to obtain biomineralized nanobiomaterials to enable its applicability as ``scaffold{''} to cellular support and consequent bone tissue formation, accelerating the osseointegration. Layer densification has been achieved due to polycrystalline nanoapatites deposition on surface and between the biomineralized nHAp/VAMWCNT-O-2 nanocomposites, without any heat treatment. Therefore, through its characteristics and properties these nanocomposite applications can be considered extremely viable for acceleration of in vivo regenerative processes. (AU)

FAPESP's process: 12/02159-4 - In vitro analysis of the biomineralization and cell proliferation on nanohydroxyapatite/vertically aligned carbon nanotube scaffolds
Grantee:Tayra Rodrigues Brazil
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 11/20345-7 - Study of nanoparticle-incorporated diamond-like carbon films for biomedical applications
Grantee:Fernanda Roberta Marciano
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 11/17877-7 - Development of new polymeric scaffolds by electrospinning technique with incorporation of vertically aligned carbon nanotubes and nanohidroxyapatite for bone tissue regeneration
Grantee:Anderson de Oliveira Lobo
Support type: Research Grants - Young Investigators Grants