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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Effects of Two Different Doses of Calcium Lactate on Blood pH, Bicarbonate, and Repeated High-Intensity Exercise Performance

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Painelli, Vitor de Salles [1] ; da Silva, Rafael Pires [1] ; de Oliveira Junior, Odilon Marques [1] ; de Oliveira, Luana Farias [1] ; Benatti, Fabiana Braga [1] ; Rabelo, Tobias [1] ; Limongi Franca Guilherme, Joao Paulo [1] ; Lancha Junior, Antonio Herbert [1] ; Artioli, Guilherme Giannini [1]
Total Authors: 9
[1] Univ Sao Paulo, Lab Appl Nutr & Metab, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Web of Science Citations: 4

We investigated the effects of low- and high-dose calcium lactate supplementation on blood pH and bicarbonate (Study A) and on repeated high-intensity performance (Study B). In Study A, 10 young, physically active men (age: 24 +/- 2.5 years; weight: 79.2 +/- 9.45 kg; height: 1.79 +/- 0.06 m) were assigned to acutely receive three different treatments, in a crossover fashion: high-dose calcium lactate (HD: 300 body mass), low-dose calcium lactate (LD: 150 body mass) and placebo (PL). During each visit, participants received one of these treatments and were assessed for blood pH and bicarbonate 0, 60, 90, 120, 150, 180, and 240 mm following ingestion. In Study B, 12 young male participants (age: 26 +/- 4.5 years; weight: 82.0 +/- 11.0 kg; height: 1.81 +/- 0.07 m) received the same treatments of Study A. Ninety minutes after ingestion, participants underwent 3 bouts of the upper-body Wingate test and were assessed for blood pH and bicarbonate 0 and 90 min following ingestion and immediately after exercise. In Study A, both BD and LD promoted slight but significant increases in blood bicarbonate (31.47 +/- 1.57 and 31.69 +/- 1.04 mmol.L-1, respectively) and pH levels (7.36 +/- 0.02 and 7.36 +/- 0.01, respectively), with no effect of PL. In Study B, total work done, peak power, mean power output were not affected by treatments. In conclusion, low- and high-dose calcium lactate supplementation induced similar, yet very discrete, increases in blood pH and bicarbonate, which were not sufficiently large to improve repeated high-intensity performance. (AU)

FAPESP's process: 12/22516-6 - Polygenic profile of Brazilian athletes: distribution of polymorphisms associated with physical performance
Grantee:João Paulo Limongi França Guilherme
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 10/11221-0 - Artificial elevation of muscle buffering capacity: effects upon muscle performance and function and underlying mechanisms
Grantee:Antonio Herbert Lancha Junior
Support type: Regular Research Grants
FAPESP's process: 13/04806-0 - Effects of 12 weeks of high-intensity intermittent training on intramuscular carnosine concentrations
Grantee:Vitor de Salles Painelli
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 11/17059-2 - Effects of beta-alanine supplementation combined or not with sodium bicarbonate on intermittent anaerobic performance
Grantee:Guilherme Giannini Artioli
Support type: Scholarships in Brazil - Post-Doctorate