Program of population studies on the consumption of ultraprocessed foods and health

• Grant number: 22/05636-0
• Support Opportunities: Research Projects - Thematic Grants
• Start date: June 01, 2023
• End date: May 31, 2028
• Field of knowledge: Health Sciences - Nutrition - Nutritional Analysis of Population
• Principal Investigator: Carlos Augusto Monteiro
• Grantee: Carlos Augusto Monteiro
• Host Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Pesquisadores principais: Renata Bertazzi Levy
• Associated researchers: Aluisio Jardim Dornellas de Barros ; Bruce Bartholow Duncan ; Catarina Machado Azeredo ; Christopher Joseph Millett ; Eduardo Augusto Fernandes Nilson ; Eurídice Martínez Steele ; Leandro Fórnias Machado de Rezende ; Luiz Augusto Marcondes Fonseca ; Maria Inês Schmidt ; Maria Laura da Costa Louzada ; Neha Khandpur ; Niyati Parekh ; Priscila Pereira Machado ; Rafael Moreira Claro
• Associated research grant(s): 23/18226-7 - Longitudinal associations of physical activity, ultraprocessed food consumption and non-communicable diseases., AV.EXT
• Associated scholarship(s): 25/11296-5 - Consumption of ultra-processed foods according to the sociodemographic profile of the NutriNet Brazil study population., BP.IC; 25/09555-2 - Consumption of ultra-processed foods and its association with the incidence of type 2 diabetes mellitus and chronic kidney disease in the NutriNet Brasil Cohort., BP.PD; 24/17436-0 - Food biodiversity and its association with health outcomes in the NutriNet Brasil cohort, BP.PD; + associated scholarships 24/17640-7 - Influence of diet and physical activity on the risk of cardiometabolic diseases resulting from depressive disorders, BP.PD; 24/06428-7 - Prospective Associations between Consumption of Ultra-Processed Foods, Dietary Inflammatory Index and Excessive Weight Gain in the NutriNet-Brazil Study, BP.DR; 24/17553-7 - Effect of a Brazilian diet-based digital health intervention on preventing weight gain and depressive symptoms: The PREDIBRA Clinical Trial, BP.DR; 24/23369-4 - Prevalence of obesity according to the sociodemographic profile of the population in the NutriNet Brasil Study, BP.IC; 24/21042-8 - Prevalence of Stroke According to the Sociodemographic Profile of the Population in the Nutrinet Brazil Study, BP.IC; 24/07662-3 - Effect of a digital health intervention based on the Dietary Guidelines for the Brazilian Population on diet quality: a randomized clinical trial nested to the NutriNet-Brasil Coorth Study, BP.PD; 24/04234-0 - Diet quality scores based on the Nova classification: innovation in monitoring healthy and sustainable diets and predicting the risk of non-communicable chronic diseases, BP.PD; 23/11159-2 - Food processing and cardiometabolic risk in overweight and obese adults: a prospective study in the NutriNet-Brazil cohort, BP.DR; 23/18328-4 - Consumption of ultra-processed foods and its association with the incidence of inflammatory bowel diseases in the NutriNet Brasil Cohort, BP.PD; 24/04267-6 - Consumption of ultra-processed foods and its association with incidence of type 2 diabetes mellitus and chronic renal failure in the NutriNet Brasil Cohort., BP.PD; 24/04278-8 - Consumption of ultra-processed foods and its association with incidence of arterial hypertension and all-cause mortality in the NutriNet Brasil Cohort., BP.PD; 24/04265-3 - Consumption of ultra-processed foods and its association with the incidence of dyslipidemia and cardiovascular diseases in the NutriNet Brasil Cohort, BP.PD; 24/00588-2 - SCIENTIFIC DISCLOSURE OF THE NUTRINET BRAZIL COHORT: DESIGN, MAGNITUDE, HYPOTHESES, OBJECTIVES, AND INITIAL RESULTS., BP.JC; 24/00590-7 - SCIENTIFIC DISCLOSURE OF THE NUTRINET BRAZIL COHORT: STUDY POPULATION PROFILE., BP.JC; 24/00624-9 - SCIENTIFIC DISCLOSURE OF THE NUTRINET BRAZIL COHORT: STUDY POPULATION PROFILE., BP.JC; 24/00626-1 - SCIENTIFIC DISCLOSURE OF THE NUTRINET BRAZIL COHORT: DESIGN, MAGNITUDE, HYPOTHESES, OBJECTIVES, AND INITIAL RESULTS., BP.JC; 23/16144-3 - 'Creation and organization of the Nutrinet Brasil Study databases' of the project 'Program for Population Studies on Consumption of Ultra-Processed Foods and Health', BP.TT; 23/17667-0 - Prevalence of chronic renal failure according to the sociodemographic profile of the population in the NutriNet Brasil Study, BP.IC; 23/15487-4 - Linkage of NutriNet Brasil Study database with other databases from Brazilian morbidity and mortality registration systems, BP.TT; 23/07659-0 - Prevalence of inflamatory bowel diseases according to sociodemographic profile of the population of the NutriNet Brasil Study, BP.IC; 23/07692-7 - Prevalence of arterial hypertension according to sociodemographic profile of the population in the Nutrinet Brasil Study, BP.IC; 23/07985-4 - Type 2 diabetes mellitus prevalence according to sociodemographic profile at NutriNet-Brasil cohort study, BP.IC; 23/08274-4 - Prevalence of obesity according to sociodemographic profile of the population in the Nutrinet Brasil Study, BP.IC - associated scholarships

Abstract

This thematic project (2022-2027) continues a previous project (2016-2021) about the consumption of ultra-processed foods and health in seven countries (including Brazil), which resulted in more than one hundred scientific articles that, published in high-impact international journals, had great influence on the science of nutrition and on the development of food and nutrition policies (in Brazil and other countries). In the previous project, the objective was to evaluate the impact of ultra-processed food consumption on the nutritional dietary quality and, secondarily, on the prevalence of obesity. The present project aims to execute an ambitious research program composed of five studies. The first involves following 100,000 participants of the NutriNet Brasil Cohort and studying, in this cohort, the prospective association between consumption of ultra-processed foods and the incidence of chronic diseases that currently account for most of the total burden of diseases in Brazil (hypertension, dyslipidemia, diabetes, cardiovascular, gastrointestinal and renal diseases, depression, and diet-related cancers). The second involves studying the same associations in ten other cohorts in Brazil (ELSA and Pelotas), the United States (Harvard and Framingham), the United Kingdom (UK Biobank and ALSPAC), Netherlands (Rotterdam Study, Alpha Omega Cohort, Generation R Study) and Australia (Melbourne) in collaboration with research teams from these countries. The third, also collaborative, will estimate the total disease burden attributable to the consumption of ultra-processed foods in ten countries. The fourth involves the pioneering assessment of the environmental impact associated with the consumption of ultra-processed products. The fifth will validate innovative data collection instruments to assess the consumption of ultra-processed foods. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

NILSON, EDUARDO A. F.; DELPINO, FELIPE MENDES; BATIS, CAROLINA; MACHADO, PRISCILA PEREIRA; MOUBARAC, JEAN-CLAUDE; CEDIEL, GUSTAVO; CORVALAN, CAMILA; FERRARI, GERSON; RAUBER, FERNANDA; MARTINEZ-STEELE, EURIDICE; et al. Premature Mortality Attributable to Ultraprocessed Food Consumption in 8 Countries. AMERICAN JOURNAL OF PREVENTIVE MEDICINE, v. 68, n. 6, p. 9-pg., 2025-06-01. (22/05636-0)

CAROLINE DOS SANTOS COSTA; FRANCINE SILVA DOS SANTOS; KAMILA TIEMANN GABE; EURÍDICE MARTINEZ STEELE; FERNANDA HELENA MARROCOS-LEITE; NEHA KHANDPUR; FERNANDA RAUBER; MARIA LAURA DA COSTA LOUZADA; RENATA BERTAZZI LEVY. Description and performance of two diet quality scores based on the Nova classification. Revista de Saúde Pública, v. 58, 2024-11-25. (22/05636-0)

WERNECK, ANDRE O.; STEELE, EURIDICE M.; DELPINO, FELIPE M.; LANE, MELISSA M.; MARX, WOLFGANG; JACKA, FELICE N.; STUBBS, BRENDON; TOUVIER, MATHILDE; SROUR, BERNARD; LOUZADA, MARIA LC.; et al. Adherence to the ultra-processed dietary pattern and risk of depressive outcomes: Findings from the NutriNet Brasil cohort study and an updated systematic review and meta-analysis. Clinical Nutrition, v. 43, n. 5, p. 10-pg., 2024-04-12. (19/24124-7, 22/05636-0)