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Degradation of hyperphosphorylated tau and organelles trafficking during neurodegenerative processes linked to protein aggregation in hypoccampal cell cultures

Grant number: 11/06434-7
Support Opportunities:Regular Research Grants
Duration: July 01, 2011 - June 30, 2013
Field of knowledge:Biological Sciences - Morphology - Cytology and Cell Biology
Principal Investigator:Merari de Fátima Ramires Ferrari
Grantee:Merari de Fátima Ramires Ferrari
Host Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Articles published in Agência FAPESP Newsletter about the research grant:
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CHAVES, RODRIGO S.; MELO, THAIANY Q.; D'UNHAO, ALINE M.; FARIZATTO, KAREN L. G.; FERRARI, MERARI F. R.. Dynein c1h1, dynactin and syntaphilin expression in brain areas related to neurodegenerative diseases following exposure to rotenone. ACTA NEUROBIOLOGIAE EXPERIMENTALIS, v. 73, n. 4, p. 541-556, . (08/04480-9, 09/12200-9, 11/00478-2, 11/06434-7)
LIMA, NATHAN C. R.; MELO, THAIANY Q.; SAKUGAWA, ANDRESSA Y. S.; MELO, KARLA P.; FERRARI, MERARI F. R.. Restoration of Rab1 Levels Prevents Endoplasmic Reticulum Stress in Hippocampal Cells during Protein Aggregation Triggered by Rotenone. Neuroscience, v. 419, p. 5-13, . (17/14273-0, 13/08028-1, 15/10892-1, 11/06434-7, 15/18961-2)
MELO, KARLA P.; SILVA, CAROLLINY M.; ALMEIDA, MICHAEL F.; CHAVES, RODRIGO S.; MARCOURAKIS, TANIA; CARDOSO, SANDRA M.; DEMASI, MARILENE; NETTO, LUIS E. S.; FERRARI, MERARI F. R.. Mild Exercise Differently Affects Proteostasis and Oxidative Stress on Motor Areas During Neurodegeneration: A Comparative Study of Three Treadmill Running Protocols. NEUROTOXICITY RESEARCH, v. 35, n. 2, p. 410-420, . (13/08028-1, 15/18961-2, 11/06434-7, 11/15281-0, 11/15283-2, 17/14273-0, 11/00478-2)
LIMA, RAQUEL S.; CARRETTIERO, DANIEL C.; FERRARI, MERARI F. R.. BAG2 prevents Tau hyperphosphorylation and increases p62/SQSTM1 in cell models of neurodegeneration. MOLECULAR BIOLOGY REPORTS, v. N/A, p. 13-pg., . (11/06434-7, 13/08028-1, 18/07592-4, 17/24722-6, 16/04409-9)
MELO, THAIANY Q.; PALMA, FLAVIO R.; GOMES, FERNANDO; NETTO, LUIS E. S.; FERRARI, MERARI F. R.. Absence of Gem1 (mammalian Miro/Rhot) mitigates alpha-synuclein toxicity in a yeast model of Parkinson's disease. Molecular and Cellular Neuroscience, v. 122, p. 9-pg., . (13/08028-1, 11/06434-7, 15/18961-2, 18/07592-4)
MELO, THAIANY QUEVEDO; COPRAY, SJEF J. C. V. M.; FERRARI, MERARI F. R.. Alpha-Synuclein Toxicity on Protein Quality Control, Mitochondria and Endoplasmic Reticulum. Neurochemical Research, v. 43, n. 12, p. 2212-2223, . (13/08028-1, 11/06434-7, 15/18961-2)
MELO, THAIANY Q.; D'UNHAO, ALINE M.; MARTINS, STEPHANIE A.; FARIZATTO, KAREN L. G.; CHAVES, RODRIGO S.; FERRARI, MERARI F. R.. Rotenone-Dependent Changes of Anterograde Motor Protein Expression and Mitochondrial Mobility in Brain Areas Related to Neurodegenerative Diseases. Cellular and Molecular Neurobiology, v. 33, n. 3, p. 327-335, . (08/04480-9, 11/00478-2, 09/12200-9, 11/05576-2, 11/06434-7)

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