| Grant number: | 13/02203-6 |
| Support Opportunities: | Regular Research Grants |
| Start date: | August 01, 2013 |
| End date: | July 31, 2015 |
| Field of knowledge: | Agronomical Sciences - Food Science and Technology - Food Engineering |
| Principal Investigator: | Julian Martínez |
| Grantee: | Julian Martínez |
| Host Institution: | Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
| City of the host institution: | Campinas |
| Associated researchers: | Camila Alves de Rezende ; Maria Angela de Almeida Meireles Petenate ; Maurício Ariel Rostagno |
Abstract
This project is dedicated to the construction of new equipments for the processing of natural products using high pressure fluids, such as carbon dioxide (CO2) and water. The use of pressurized solvents is an alternative to toxic organic solvents, or to techniques that require high temperatures. The equipments to be built will address the extraction and nanoparticle formation of bioactive compounds from raw materials or food industry byproducts, both of vegetal sources, and the synthesis of esters by means of reactions with the possibility of using enzymes. In the extraction step supercritical CO2 (SFE) and pressurized water (PLE) extractions will be performed. Indeed, ultrasound will be applied during the extractions in order to accelerate the processes and increase their yields. The extracts obtained by SFE and PLE, with or without ultrasound, will be lead to encapsulation procedures, which will be performed through methods that use supercritical CO2 as antisolvent (SAS and SFEE). The produced particles will be evaluated in terms of their size, uniformity, shape, concentration and stability of their bioactive compounds. The kinetics of controlled release of the compounds will be evaluated, as well as their stability in the liberation mean. Finally, the biological activities of the encapsulated products will be evaluated by specific tests. The synthesis of esters will be performed using supercritical CO2 as reaction medium, alcohols, sugars, fatty acids and terpenes as substrates, and immobilized lipases ad catalyzers, leading to sugar or terpenic esters as products. The processes of extraction, particle formation and release will have their mechanisms studied by means of mathematical modeling, dealing with thermodynamic and kinetic issues. The performing of the proposed processes will demand the construction of four equipments, being one of supercritical extraction (SFE) and pressurized liquid extraction (PLE), one of SFE and PLE assisted by ultrasound, one for particle formation by SAS and SFEE, and a high pressure reactor. Therefore, the financial resources of the present proposal concentrate in equipments, consumables and services needed to build and operate those units. (AU)
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PROCESSO DE OBTENÇÃO DE ÉSTERES DE AROMAS CATALISADOS POR ENZIMAS IMOBILIZADAS EM DIÓXIDO DE CARBONO SUPERCRÍTICO, ÉSTERES DE AROMAS ASSIM OBTIDOS E USO BR 10 2017 012756 7 - Universidade Estadual de Campinas Unicamp . Julian Martínez; Philipe Dos Santos - January 2017, 01
PROCESSO DE OBTENÇÃO DE LIGNANAS E USO DAS LIGNANAS BR 10 2017 021930 5 - Universidade Estadual de Campinas Unicamp . Rúbner Gonçalves Pereira; Julian Martinez; Vera Lúcia Garcia; Renato Naohiro Nakamura - January 2017, 01