Advanced search
Start date
Betweenand

The effect of ovariectomy on dental replantation: a histomorphometric and immunohistochemistry analysis in rats

Grant number: 10/12593-8
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): October 01, 2010
Effective date (End): September 30, 2013
Field of knowledge:Health Sciences - Dentistry - Oral and Maxillofacial Surgery
Principal researcher:Sonia Regina Panzarini
Grantee:Heloisa Fonseca Marão
Home Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil
Associated scholarship(s):12/08254-9 - The effect of ovariectomy on dental replantation: micro-computed tomography analysis, BE.EP.DR

Abstract

Osteoporosis is an illness that is frequently encountered by dental surgeons in the clinic, and is caused by disequilibrium between processes of bone tissue formation and absorption. With the increasing life expectancy of the global population, more researchers are focusing on geriatrics, in order to provide the population with a healthier aging process. Individuals with osteoporosis are susceptible to both long bone and hip fractures, and dento-alveolar trauma. Considering the shortage of literature in the study of dento-alveolar trauma in individuals with osteoporosis, the aim of this study was to analyze the repair process in immediate dental replanting and its possible association with this systemic alteration (osteoporosis). A well-established experimental model, recommended by the Food and Drug Administration (FDA), was used for this analysis, i.e. ovariectomy (OVX) in rats. The project consists of two experimental groups: group I: sham rats, and group II: OVX rats. The upper right incisor of all animals will be submitted to extraction and immediate tooth replantation. Evaluation will be done by histomorphometric analysis to verify and measure external radicular resorption and immunohistochemical by the balance of proteins PCNA, RUNX-2, CASPASE-3, OPG and TRAP. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items
VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MARAO, HELOISA FONSECA; MAO, JEREMY J.; CASATTI, CLAUDIO APARECIDO; COELHO, PAULO G.; ERVOLINO, EDILSON; ZHOU, JIAN; DA SILVA, VANESSA FERREIRA; PANZARINI, SONIA REGINA. Effects of ovariectomy on periodontal tissues following tooth replantation. ARCHIVES OF ORAL BIOLOGY, v. 65, p. 9-16, MAY 2016. Web of Science Citations: 0.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
MARÃO, Heloisa Fonseca. Efeito da ovariectomia sobre os tecidos periodontais após o reimplante dentário imediato : análise histomorfométrica, imunoistoquímica e micro-ct em ratas. 2013. 123 f. Doctoral Thesis - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Odontologia (Campus de Araçatuba).

Please report errors in scientific publications list by writing to: cdi@fapesp.br.