Development of electrochemistry sensors and methods of solid phase extraction based in biomimetic systems for analysis of environmental pollutants

• Grant number: 11/03008-7
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): June 01, 2011
• Effective date (End): July 31, 2014
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Maria Del Pilar Taboada Sotomayor
• Grantee: Ademar Wong
• Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

This project aims the development of an analytical method based on bi-biomimetic systems for the determination of pesticides carbofuran, diuron and 2,4-D, which are widely used in the country in plantations of corn, cotton, rice, wheat, cane sugar, potato, tomato, among others. The construction of the bi-biomimetic systems will be based in the junction of two analytical tools that have been shown to be promising in the sensitive and selective determination of analytes different; biomimetic sensors and molecularly imprinted polymers (MIP). In this project, for the construction of biomimetic sensors will be employed compounds analogous to the active site of P450 enzymes structure, and in this case the metal-based phthalocyanine and porphyrin complexes fit perfectly. These complexes are immobilized on the surface of glassy carbon electrodes and carbon paste. On the other hand, the molecularly imprinted polymers or MIPs ("Molecularly Imprinted Polymers"), which will be characterized by scanning atomic force microscopy (AFM) electron microscopy (SEM), and can be directly fixed on the surfaces of electrodes for development of biomimetic, or sensors, can be used as adsorbent materials in solid phase extraction systems (MISPE) in order to carry out a clean-up and pre-concentration of samples to be analyzed later by biomimetic sensors built previously. It is expected that this design biomimetic systems developed to become a real alternative tool in the analysis of pesticides in the environment and in food and the coupled online with the biomimetic sensors MISPE, to obtain bi-biomimetic systems which can ensure a methodology for analyzing highly sensitive, selective and applicable.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ADEMAR WONG; LUIZ D. MARESTONI; MARIA D. P. T. SOTOMAYOR. Monitoring of diclofenac with biomimetic sensor in batch and FIA systems. Journal of the Brazilian Chemical Society, v. 25, n. 7, p. 1283-1291, 2014-07-00. (11/03008-7)

WONG, ADEMAR; FOGUEL, MARCOS VINICIUS; KHAN, SABIR; DE OLIVEIRA, FERNANDA MIDORI; TEIXEIRA TARLEY, CESAR RICARDO; SOTOMAYOR, MARIA D. P. T.. DEVELOPMENT OF AN ELECTROCHEMICAL SENSOR MODIFIED WITH MWCNT-COOH AND MIP FOR DETECTION OF DIURON. Electrochimica Acta, v. 182, p. 122-130, NOV 10 2015. (11/03008-7, 14/25264-3)

WONG, ADEMAR; DE OLIVEIRA, FERNANDA MIDORI; TEIXEIRA TARLEY, CESAR RICARDO; TABOADA SOTOMAYOR, MARIA DEL PILAR. Study on the cross-linked molecularly imprinted poly(methacrylic acid) and poly(acrylic acid) towards selective adsorption of diuron. REACTIVE & FUNCTIONAL POLYMERS, v. 100, p. 26-36, MAR 2016. (11/03008-7)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

WONG, Ademar. Desenvolvimento de sensores eletroquímicos e métodos de extração em fase sólida baseados em sistemas biomiméticos para análise de poluentes ambientais. 2014. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Instituto de Química. Araraquara Araraquara.