Development of analytical tools based on electronic tongues for simultaneous detection of bacterial threats

• Grant number: 15/01770-0
• Support Opportunities: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): June 01, 2015
• Effective date (End): February 28, 2019
• Field of knowledge: Physical Sciences and Mathematics - Physics - Condensed Matter Physics
• Acordo de Cooperação: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Osvaldo Novais de Oliveira Junior
• Grantee: Deivy Wilson Masso
• Host Institution: Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Associated research grant: 13/14262-7 - Nanostructured films from biologically-relevant materials, AP.TEM

Abstract

The identification of bacteria in food, water and biological samples is made through complicated or lengthy procedures, with confirmation of the bacteria presence normally arriving late. In this study we shall develop advanced analytical methods based on the electronic tongues (ET) paradigm for detecting bacterial threats. Use will be made of field-effect transistors and impedance spectroscopy with sensing units obtained from nanostructured membranes fabricated with self-assembled monolayers and molecular imprinted polymers (MIPs). The aim is reach an integrated approach combining advantages of ETs with sensor arrays, MIP sensors (high selectivity, chemical stability, low cost and ease of preparation), and field-effect transistors (possibility of integration in microchip and other electronic devices). The proposal also includes development of portables devices for real-time monitoring of bacteria threats through recognition of enzymes, antibodies, proteins, metabolites and toxins. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

IBANEZ-REDIN, G.; WILSON, D.; GONCALVES, D.; OLIVEIRA, JR., O. N.. Low-cost screen-printed electrodes based on electrochemically reduced graphene oxide-carbon black nanocomposites for dopamine, epinephrine and paracetamol detection. Journal of Colloid and Interface Science, v. 515, p. 101-108, APR 1 2018. (13/14262-7, 15/01770-0)

WILSON, DEIVY; MATERON, ELSA M.; IBANEZ-REDIN, GISELA; FARIA, RONALDO C.; CORREA, DANIEL S.; OLIVEIRA, JR., OSVALDO N.. Electrical detection of pathogenic bacteria in food samples using information visualization methods with a sensor based on magnetic nanoparticles functionalized with antimicrobial peptides. Talanta, v. 194, p. 611-618, MAR 1 2019. (13/14262-7, 17/12174-4, 15/01770-0)

IBANEZ-REDIN, GISELA; FURUTA, ROBERTO H. M.; WILSON, DEIVY; SHIMIZU, FLAVIO M.; MATERON, ELSA M.; REBOLHO BATISTA ARANTES, LIDIA MARIA; MELENDEZ, MATIAS E.; CARVALHO, ANDRE L.; REIS, RUI MANUEL; CHAUR, MANUEL N.; et al. Screen-printed interdigitated electrodes modified with nanostructured carbon nano-onion films for detecting the cancer biomarker CA19-9. Materials Science & Engineering C-Materials for Biological Applications, v. 99, p. 1502-1508, JUN 2019. (17/12096-3, 13/14262-7, 15/01770-0, 16/00991-5, 12/15543-7)

SILVA, ROBSON R.; RAYMUNDO-PEREIRA, PAULO A.; CAMPOS, ANDERSON M.; WILSON, DEIVY; OTONI, CAIO G.; BARUD, HERNANE S.; COSTA, CARLOS A. R.; DOMENEGUETTI, RAFAEL R.; BALOGH, DEBORA T.; RIBEIRO, SIDNEY J. L.; et al. Microbial nanocellulose adherent to human skin used in electrochemical sensors to detect metal ions and biomarkers in sweat. Talanta, v. 218, OCT 1 2020. (16/01919-6, 13/14262-7, 15/01770-0, 16/06612-6)